Therapies
Monday, October 22nd, 2012
Thrombosis Journal: October 18, 2012 Dual antiplatelet treatment with aspirin and clopidogrel is the antithrombotic treatment recommended after an acute coronary syndrome and/or coronary artery stenting. The evidence for optimal antiplatelet therapy for patients, in whom long-term treatment oral anticoagulation is mandatory, is however scarce. To evaluate the safety and efficacy of the various antithrombotic strategies […]
Therapies
Monday, October 22nd, 2012
American Heart Association, Inc.: October 15, 2012 Novel oral anticoagulants (NOACs) have been proposed as alternatives to vitamin K antagonists (VKAs) for prevention of stroke and systemic embolism (SE) in patients with atrial fibrillation (AF). Individually, NOACs were at least non-inferior to VKAs, but a clear superiority in overall and vascular mortality was not consistently proven. […]
Therapies
Monday, October 22nd, 2012
Sience Direct.: October 8, 2012 Dabigatran is a recently introduced direct thrombin inhibitor licensed for use as an oral anticoagulant for stroke prevention in non-valvular atrial fibrillation. Our prospective observational study aimed to assess the adverse effects, tolerability and patient satisfaction of dabigatran therapy in a hospital-practice population. Methods Patients starting dabigatran, after its release in […]
Therapies
Monday, October 22nd, 2012
American College of Cardiology Foundation: October 1, 2012 Year Outcomes of the Hamburg Sequential Ablation Strategy This study describes the 5-year efficacy of catheter ablation for long-standing persistent atrial fibrillation (LS-AF). Background Long-term outcome data after catheter ablation for LS-AF are limited. Methods Long-term follow-up of 56 months (range 49 to 67 months) was performed in 202 patients […]
Therapies
Monday, October 22nd, 2012
American Heart Journal: July 15, 2012. Older patients with atrial fibrillation (AF) and coronary artery disease (CAD) face high risk of stroke and bleeding with antithrombotic therapy. Balancing safe and effective use of aspirin, clopidogrel, and warfarin in this population is important. Methods From the Duke Databank for Cardiovascular Disease, we identified patients with AF […]
News
Monday, October 22nd, 2012
Neurology: October 17, 2012 We synthesized the epidemiologic evidence concerning selective serotonin reuptake inhibitor (SSRI) exposure and the risk of CNS hemorrhage. Methods: We searched for controlled observational studies comparing SSRI therapy with a control group not receiving SSRIs. We used DerSimonian and Laird fixed effect models to compute summary risk associations. Results: Intracranial hemorrhage was related to […]
News
Monday, October 22nd, 2012
Jama: October 15, 2012 We sought to develop and validate a simple clinical prediction rule for death and severe disability after acute ischemic stroke that can be used by general clinicians at the time of hospital admission. Methods We analyzed data from a registry of 9847 patients (4943 in the derivation cohort and 4904 in the […]
News
Monday, October 22nd, 2012
Environmental Health: October 15, 2012 While several studies have investigated the effects of short-term air pollution on cardiovascular disease, less is known about its effects on cerebrovascular disease, including stroke and transient ischaemic attack (TIA). The aim of the study was to assess the effects of short-term variation in air pollutants on the onset of TIA […]
News
Monday, October 22nd, 2012
Neurology: October 10, 2012 We aimed to study various measures of blood pressure (BP) in the subacute phase of ischemic stroke to determine whether any of them predicted clinical outcome. Methods: In this retrospective observational study, a consecutive series of patients hospitalized for ischemic stroke within 48 hours of onset were enrolled. The subacute stage of stroke […]
News
Monday, October 22nd, 2012
The New York Times Company: SEPTEMBER 15, 2011 Can an apple a day keep away stroke? The old adage promoting an apple a day for better health just got a boost from science. A large Dutch study has found that eating apples and pears is associated with a lower risk of stroke. The findings counter […]
