Atrial Fibrillation
Friday, August 28th, 2015
HeartRhythm, July 2015 Background Atrial fibrillation (AF) is associated with an increased risk of stroke and death. Uniform utilization of appropriate therapies for AF may help reduce those risks. Objective We sought to determine whether significant race and sex differences exist in the treatment of newly diagnosed AF in Medicare beneficiaries.… Conclusion Race and sex […]
Atrial Fibrillation, Guidelines
Friday, August 28th, 2015
J Am Heart Assoc, 6 April 2015 Background Although guidelines for antiarrhythmic drug therapy in atrial fibrillation (AF) were published in 2006, it remains uncertain whether adherence to these guidelines affects patient outcomes.… Conclusions Adherence to published guidelines in the antiarrhythmic management of AF is associated with improved patient outcomes. Read more.
Atrial Fibrillation, Guidelines
Friday, August 28th, 2015
Circ Cardiovasc Qual Outcomes, 2 September 2014 Background—Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is a cause of stroke, heart failure, and death. Guideline-based treatment can improve outcomes in AF. Unfortunately, adherence to these guidelines is low. Get With The Guidelines is a hospital-based performance initiative, which has been shown to […]
Atrial Fibrillation
Thursday, August 7th, 2014
J Am Coll Cardiol.: August 2014 Background Transcatheter left atrial appendage (LAA) ligation may represent an alternative to oral anticoagulation for stroke prevention in atrial fibrillation. Objectives This study sought to assess the early safety and efficacy of transcatheter ligation of the LAA for stroke prevention in atrial fibrillation. Methods This was a retrospective, multicenter study of consecutive patients undergoing LAA […]
Atrial Fibrillation
Thursday, August 7th, 2014
Heart rhythm journal: August 04, 2014 Background Traditional mapping of atrial fibrillation (AF) is limited by changing electrogram morphologies and variable cycle lengths. Objective We tested the hypothesis that morphology recurrence plot analysis would identify sites of stable and repeatable electrogram morphology patterns. Methods AF electrograms recorded from left atrial (LA) and right atrial (RA) sites […]
Atrial Fibrillation
Thursday, August 7th, 2014
Heart rhythm journal: August 04, 2014 Background The risk of acute myocardial infarction (AMI) in patients with atrial fibrillation (AF) having a CHA2DS2-VASc score of 0 (for males) or 1 (for females) has not been previously investigated. Objective The goal of the present study was to compare the risk of AMI among AF and non-AF subjects […]
Atrial Fibrillation
Thursday, August 7th, 2014
JAMA: August 2014 Despite the introduction of several novel oral anticoagulants, warfarin remains the most widely used anticoagulation agent worldwide. Physicians have extensive experience with warfarin, it is inexpensive, its effects are easily reversible, and its activity can be monitored with a simple blood test. However, warfarin has a narrow therapeutic index and requires active […]
Atrial Fibrillation
Thursday, August 7th, 2014
CIRCGENETICS: August 1, 2014 Background—Genome-wide association studies (GWAS) have shown that the common single nucleotide polymorphism (SNP) rs6800541 located in SCN10A, encoding the voltage-gated Nav1.8 sodium channel, is associated with PR−interval prolongation and atrial fibrillation (AF). SNP rs6800541 is in high linkage disequilibrium with the non-synonymous variant in SCN10A, rs6795970 (V1073A, r2=0.933). We aim to determine whether common […]
Atrial Fibrillation
Thursday, August 7th, 2014
Heart rhythm journal: July 30, 2014 Background Thromboembolic complications remain one of the most severe adverse events associated with catheter ablation of atrial fibrillation (AF) but there are limited data on those events. Objective The aim of this study was to evaluate the incidence, characteristics and risk factors of thromboembolic complications after AF ablation. Methods Cerebral […]
Atrial Fibrillation
Thursday, August 7th, 2014
Wiley: 7/28/14 Abstract Objective We examined the association of rs7626962 (S1103Y) or rs7629265, a variant in high linkage disequilibrium with S1103Y (r2 = 0.87–1), with sudden cardiac death (SCD) and atrial fibrillation (AF) among African Americans. Background The SCN5A missense variant S1103Y has been associated with SCD among African Americans in small case-control studies, but larger population-based studies are […]
