In this first episode of Voice of Stroke, we examine three key trials presented at ISC 2026 that challenge how we define time boundaries in acute stroke care.

This episode explores:

• Extending intravenous thrombolysis beyond 4.5 hours in non-large vessel occlusion stroke (OPTION)
• Tenecteplase within 24 hours for basilar artery occlusion (TRACE-5)
• Ultra-early recombinant factor VIIa in intracerebral haemorrhage (FASTEST)

Together, these trials refine our understanding of patient selection, risk, and benefit across ischaemic and haemorrhagic stroke.

This month’s Voice of Stroke episode was written by Linxin Li, Editor-in-Chief of the Voice of Stroke Podcast.

Read the full transcript here

Check out this episode!

<p>The post Beyond the Window – What ISC 2026 Tells Us About Treating Stroke Earlier or Later first appeared on European Stroke Organisation.</p>

Welcome to Voice of Stroke, brought to you by the European Stroke Organisation.
Your fast, reliable update on the science driving stroke care forward.

Each month, we spotlight key papers from the world’s leading journals and discuss how it can inform and refine clinical practice.

From breakthrough randomised controlled trials to cross-disciplinary insights, Voice of Stroke brings you concise, evidence-based takeaways — straight from the front lines of research.

Check out this episode!

<p>The post Welcome to the ESO Voice of Stroke Podcast first appeared on European Stroke Organisation.</p>