Eurek Alert: March 1, 2012. Older women whose diets include a substantial amount of trans fats are more likely than their counterparts to suffer an ischemic stroke, a new study shows. However, the risk of stroke associated with trans fat intake was lower among women taking aspirin, according to the findings from University of North Carolina […]
Pharma Times: WORLD NEWS KEVIN GROGAN | MARCH 01, 2012. Bristol-Myers Squibb and Pfizer will have to wait a bit longer before getting US approval for their anti-clotting drug Eliquis. The US Food and Drug Administration has extended the action date by three months for the New Drug Application for Eliquis (apixaban) for the prevention of stroke […]
The New England Journal of Medicine: Daniel B. Kramer, M.D., Shuai Xu, M.Sc., and Aaron S. Kesselheim, M.D., J.D., M.P.H., N Engl J Med 2012; 366:848-855 – March 1, 2012. Millions of patients worldwide depend on an ever-widening array of medical devices for the diagnosis and management of disease. In the United States, the Food and Drug […]
New Scientist: February 29, 2012. A DRUG which minimises brain damage when given three hours after stroke has proved successful in monkeys and humans. A lack of oxygen in the brain during a stroke can cause fatal brain damage. There is only one approved treatment – tissue plasminogen activator – but it is most effective when administered within […]
Medical Xpress) — A family of proteins named after Popeye play an essential role in allowing the heart to respond to stress, according to a study published today in the Journal of Clinical Investigation. The finding could help scientists develop new treatments for abnormal heart rhythms. Medical Research: February 24, 2012. Popeye domain containing proteins (Popdc for […]
Science Direct: February 13, 2012 – Annie Guérina, , Jay Linb, Mehul Jhaveric, Eric Q. Wua, Andrew P. Yua, Martin Cloutiera,Genevieve Gauthiera, Joseph S. Alpertd. Abstract Background This retrospective cohort study compared rates of treatment persistence, incidences of de novo stroke, arterial embolism, and hemorrhage/bleeding, and healthcare resource use and costs between atrial fibrillation/flutter (AF/AFL) patients receiving concomitant warfarin (W) + amiodarone (A) or warfarin + other antiarrhythmic […]
Stroke.ahajournals: February 3, 2012 – Stroke.ahaJournals: Hooman Kamel, MD; S. Claiborne Johnston, MD, PhD; J. Donald Easton, MD; Anthony S. Kim, MD, MAS Abstract Background and Purpose—The cost-effectiveness of dabigatran for stroke prevention in patients with atrial fibrillation and prior stroke or transient ischemic attack has not been directly assessed. Methods—A Markov decision model was constructed using data from the Randomized Evaluation […]
Stopafib: By Peggy Noonan – February 29, 2012 Summary: Stroke deaths have dropped dramatically in recent years, but a black-white racial disparity remains. High blood pressure, diabetes, atrial fibrillation, and heart disease were found to be responsible for about half of this disparity, but the other half remains a mystery. Reading time is approximately 6-8 minutes Although the total […]
Canadian Medical Association: Feb. 27, 2012 – Irene Marzona, Martin O’Donnell, Koon Teo, Peggy Gao, Craig Anderson, Jackie Bosch, Salim Yusuf. Abstract Background: The role of atrial fibrillation in cognitive impairment and dementia, independent of stroke, is uncertain. We sought to determine the association of atrial fibrillation with cognitive and physical impairment in a large group of patients at high cardiovascular risk. Methods: We […]
Plosone: Feb. 23, 2012 – Jessica T. Delaney1, Janina M. Jeff2,3, Nancy J. Brown1,4, Mias Pretorius5, Henry E. Okafor6, Dawood Darbar1, Dan M. Roden1,4, Dana C. Crawford2,3* Abstract Top Background Despite a greater burden of risk factors, atrial fibrillation (AF) is less common among African Americans than European-descent populations. Genome-wide association studies (GWAS) for AF in European-descent populations have identified three predominant genomic regions […]
