Clinical Trials
Wednesday, October 5th, 2016
Stroke, 1 October 2015 Background and Purpose—Emergency medical services routing of patients with acute stroke to designated centers may increase the proportion of patients receiving care at facilities meeting national standards and augment recruitment for prehospital stroke research. … Conclusions—The establishment of a regionalized emergency medical services system of acute stroke care dramatically increased the proportion of patients […]
Clinical Trials
Wednesday, October 5th, 2016
JAMA Neurol, February 2016 Importance Intra-arterial treatment (IAT) for acute ischemic stroke caused by intracranial arterial occlusion leads to improved functional outcome in patients treated within 6 hours after onset. The influence of treatment delay on treatment effect is not yet known. Objective To evaluate the influence of time from stroke onset to the start of […]
Clinical Trials
Wednesday, October 5th, 2016
Trials, 18 December 2015 Background Effective recruitment is an essential element of successful research but notoriously difficult to achieve. This article examines health care professionals’ views on the factors influencing decision-making regarding referral to a stroke rehabilitation trial. … Conclusions Patient- and professional-related factors were the most frequent influence on clinicians’ recruitment decisions, which often had a ‘gate-keeping’ […]
Clinical Trials
Wednesday, October 5th, 2016
Stroke, 1 October 2015 Background and Purpose—The Stroke Health and Risk Education Project was a cluster-randomized, faith-based, culturally sensitive, theory-based multicomponent behavioral intervention trial to reduce key stroke risk factor behaviors in Hispanics/Latinos and European Americans. … Conclusions—This multicomponent behavioral intervention targeting stroke risk factors in predominantly Hispanics/Latinos was effective in increasing fruit and vegetable intake, reaching its […]
Clinical Trials
Wednesday, October 5th, 2016
Stroke, 1 October 2015 Background and Purpose—Central poststroke pain is a chronic neuropathic disorder that follows a stroke. Current research on its management is limited, and no review has evaluated all therapies for central poststroke pain. … Conclusions—Our findings are inconsistent with major clinical practice guidelines; the available evidence suggests no beneficial effects of any therapies that researchers […]
Clinical Trials
Wednesday, October 5th, 2016
J Am Heart Assoc, 24 August 2015 Background The latest guidelines do not make clear recommendations on the selection of antiplatelet therapies for long-term secondary prevention of stroke. We aimed to integrate the available evidence to create hierarchies of the comparative efficacy and safety of long-term antiplatelet therapies after ischemic stroke or transient ischemic attack. … Conclusions Long-term […]
Clinical Trials
Friday, August 28th, 2015
Stroke, 16 July 2015 Background and Purpose—The National Institutes of Health policy calls for the inclusion of under-represented groups, such as women and minorities, in clinical research. Poor minority recruitment and retention in stroke clinical trials remain a significant challenge limiting safety and efficacy in a general population. Previous research examines participant barriers to clinical […]
Clinical Trials
Friday, August 28th, 2015
Stroke, 9 July 2015 Background and Purpose—It is unknown whether women and men with acute ischemic stroke respond similar to an antioxidant regimen administered in combination with thrombolysis. Here, we investigated the independent effect of sex on the response to uric acid (UA) therapy in patients with acute stroke treated with alteplase.… Conclusions—In women with […]
Clinical Trials
Friday, August 28th, 2015
Stroke, 7 July 2015 Background and Purpose—We developed a new postdischarge system of care comprising a structured assessment covering longer-term problems experienced by patients with stroke and their carers, linked to evidence-based treatment algorithms and reference guides (the longer-term stroke care system of care) to address the poor longer-term recovery experienced by many patients with […]
Clinical Trials
Friday, August 28th, 2015
Stroke, 11 June 2015 Background and Purpose—Less than 25% of stroke patients arrive to an emergency department within the 3-hour treatment window. Stroke Warning Information and Faster Treatment (SWIFT) compared an interactive intervention (II) with enhanced educational (EE) materials on recurrent stroke arrival times in a prospective cohort of multiethnic stroke/transient ischemic attack survivors.… Conclusions—There […]
