Mdpi.com: April 5, 2012. Atrial Fibrillation (AF) is the most common sustained arrhythmia and 1/6 strokes is attributed to AF. The cornerstone of treatment remains maintaining sinus rhythm or appropriate ventricular rate control in addition to prevention of stroke. Oral anticoagulation therapy (OAC) with vitamin K antagonists (VKAs) has been the gold standard for almost […]
Content.onlinejacc.org: April 3, 2012. Objectives: The purpose of this study was to characterize patients with mitral regurgitation (MR) and atrial fibrillation (AF) treated percutaneously using the MitraClip device (Abbott Vascular, Abbott Park, Illinois) and compare the results with surgery in this population. Background: The EVEREST II (Endovascular Valve Edge-to-Edge Repair Study) randomized controlled trial compared a […]
Seniorjournal.com: April, 2, 2012. DCS can speed up word finding in healthy older people and stroke patients; helping to identify which parts of the brain should be stimulated – see video on tDCS in story April, 2, 2012 – A symposium in Chicago explores the possibilities of improving speech, memory and numerical abilities of stroke victims […]
Reuters.com: By Anna Yukhananov, SILVER SPRING, Maryland | Thu Mar 29, 2012. (Reuters) – Heart safety studies should be required for new obesity drugs, U.S. drug advisers said on Thursday, possibly adding a new hurdle to the drugs’ approval. An advisory panel to the U.S. Food and Drug Administration voted 17-6 that regulators should make companies conduct heart impact […]
A Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Substudy Crc.ahajournals.org: Feb. 28, 2012. Abstract Background—Cardiac biomarkers are strong predictors of adverse outcomes in several patient populations. We evaluated the prevalence of elevated troponin I and N-terminal pro-B-type natriuretic peptide (NT-proBNP) and their association to cardiovascular events in atrial fibrillation (AF) patients in the Randomized Evaluation […]
Philly.com: TUESDAY, APRIL 3, 2012. Watch out for dispensing mix-ups if you are taking any of the following medications: Ranexa, Prenexa and Pradaxa. These drugs are all prescribed for different reasons although their names can look and/or sound very much alike. We’ve had some close calls reported to us lately through our National Medication Error Reporting Program, […]
Stroke.ahajournals.org: March 29, 2012. Background and Purpose—Patients with stroke and transient ischemic attack (TIA) often have comparable comorbidities, but it is unclear whether they have similar rates of depression or antidepressant use. Methods—This study was a secondary analysis of a prospective cohort registry that enrolled subjects from 2006 to 2008 in the United States. Depression […]
Family Practice News: By: MITCHEL L. ZOLER, Family Practice News Digital Network, April 5, 2012. NEW ORLEANS – Nearly half of elderly patients who have an ischemic stroke also have atrial fibrillation, based on a review of 527 stroke patients aged 75 or older at a single U.S. center. Atrial fibrillation (AF) “should be meticulously searched for” […]
Biomedcentral.com: April 4, 2012. Background: Atrial fibrillation (AF) is the most common arrhythmia. The potassium current IKs is essential for cardiac repolarization. Gain-of-function mutations in KV7.1, the pore-forming alpha-subunit of the IKs channel, have been associated with AF. We hypothesized that early-onset lone AF is associated with mutations in the IKs channel regulatory subunit KCNE1. Methods: In […]
Circgenetics.ahajournals.org: April 3, 2012. Background—The left and right atria have different susceptibilities towards developing arrhythmias, with left atrial arrhythmias more commonly observed. To understand the molecular basis for such differences, we catalogued miRNA and mRNA expression differences by next generation sequencing. Methods and Results—Four human left-right atrial pairs were subjected to whole-genome expression analyses via […]
