News
Thursday, June 28th, 2012
Stroke.ahajournals.org: June 21, 2012. Background and Purpose—The purpose of this study was to investigate whether thin-slice image reconstructions of cranial nonenhanced CT scans could be used to significantly increase sensitivity for detecting intraluminal thrombus in patients with acute ischemic stroke due to proximal occlusion of the middle cerebral artery. Methods—In a prospective case series, the raw […]
News
Thursday, June 28th, 2012
Analysis of the Stroke in Young Fabry Patients Study Population Stroke.ahajournals.org: June 21, 2012. Background and Purpose—Impaired kidney function is thought to be associated with small vessel disease, outcome, and mortality in the general stroke population. Data are limited regarding young patients. The aim of this study was to investigate the association of kidney function and […]
News
Thursday, June 28th, 2012
Stroke.ahajournals.org: May 24, 2012. Background and Purpose—The present study investigated the lesion anatomy of anosognosia for visuospatial neglect resulting from right hemispheric stroke. Methods—In 63 patients, self-ratings of performance in paper-and-pencil tests were contrasted with external performance ratings. Lesion analysis was conducted on patient subgroups with different degrees of anosognosia but comparable visuospatial impairment. Results—Independent of […]
News
Thursday, June 28th, 2012
Stroke.ahajournals.org: May 10, 2012. Background and Purpose—The purpose of this study was to determine whether leukoaraiosis (LA) predicts hemorrhagic transformation and poor outcome in patients with acute ischemic stroke treated by mechanical thrombectomy. Methods—We retrospectively analyzed patients with anterior circulation stroke treated with Merci devices and identified LA in the deep white matter (DWM) and periventricular […]
News
Thursday, June 28th, 2012
Functional Outcomes, Handicap, and Quality of Life Stroke.ahajournals.org: May 8, 2012. There has been recent interest in sex differences in stroke with a focus on the first 3 months after stroke.1 We recently reported that females had more severe strokes, higher short-term mortality, and different management in comparison to males. This was explained by females’ greater age […]
Clinical Trials
Thursday, June 28th, 2012
Stroke.ahajournals.org: July 1, 2012. Background and Purpose—The purpose of this study was to test the feasibility of conducting a randomized controlled trial to study the effectiveness of self-managed computer treatment for people with long-standing aphasia after stroke. Method—In this pilot single-blinded, parallel-group, randomized controlled trial participants with aphasia were allocated to self-managed computer treatment with volunteer […]
Clinical Trials
Thursday, June 28th, 2012
The Lancet, Early Online Publication, 28 June 2012. Thrombolysis with intravenous alteplase is the only approved treatment for acute ischaemic stroke. After alteplase-induced recanalisation, reocclusion occurs in 14—34% of patients, probably because of platelet activation. Early administration of antiplatelet therapy after alteplase could reduce the risk of reocclusion and improve outcome. We compared the effects […]
Clinical Trials
Thursday, June 28th, 2012
Stroke.ahajournals.org: June 26, 2012. Background and Purpose—The DIAS-2 study was the only large, randomized, intravenous, thrombolytic trial that selected patients based on the presence of ischemic penumbra. However, DIAS-2 did not confirm the positive findings of the smaller DEDAS and DIAS trials, which also used penumbral selection. Therefore, a reevaluation of the penumbra selection strategy is […]
Clinical Trials
Thursday, June 28th, 2012
Stroke.ahajournals.org: June 26, 2012. Background and Purpose—High blood pressure is one of the main risk factors for cerebral white matter lesions (WMLs). There is limited evidence from one randomized trial that blood pressure-lowering is able to slow WML progression. We investigated whether telmisartan prevents WML progression in the imaging substudy of the Prevention Regimen for Effectively […]
Therapies
Thursday, June 28th, 2012
Jama.jamanetwork.com: June 27, 2012, Vol 307, No. 24 Context Intravenous tissue plasminogen activator (tPA) is known to improve outcomes in ischemic stroke; however, patients receiving long-term chronic warfarin therapy may face an increased risk for intracranial hemorrhage when treated with tPA. Although current guidelines endorse administering intravenous tPA to warfarin-treated patients if their international normalized ratio […]
