All you overworked and tired men and women out there should heed this warning about getting a good night’s sleep. A new study shows that getting less than six hours of sleep increases the risk of stroke. Medicaldaily.com: BY CHARLES POLADIAN | JUNE 11, 2012 All you overworked and tired men and women out there should heed this warning […]
Bmj.com: June 7, 2012. Benedict Wand and colleagues argue that the risks of cervical spine manipulation are not justified, but David Cassidy and colleagues (doi:10.1136/bmj.e3680) think it is a valuable addition to patient care Cervical spine manipulation (a high velocity, low amplitude, end range thrust manoeuvre) is a common treatment option for mechanical neck pain yet may carry […]
Stroke.ahajournals.org: June 5, 2012. Background and Purpose—States and counties in the US began implementing regional systems of acute stroke care in the first decade of the 21st century, whereby emergency medical services systems preferentially route acute stroke patients directly to primary stroke centers. The pace, geographic range, and population reach of regional stroke system implementation […]
Background and Purpose—Toward the goal of designing a clinical trial using imaging parameters to treat stroke patients with unknown onset time, we investigated the timing of changes on MRI in patients with well-defined stroke onset. Methods—Hypothesis-generating (n=85) and confirmatory (n=111) samples were scored by blinded readers for fluid-attenuated inversion recovery (FLAIR) hyperintensity in diffusion-positive regions. […]
Why Do We Need Trials and What Makes a Trial a Trial? Plosmedicine.org: Lang T, Siribaddana S (2012) Clinical Trials Have Gone Global: Is This a Good Thing? PLoS Med 9(6): e1001228. doi:10.1371/journal.pmed.1001228 Clinical trials are needed globally to reduce disease burdens by helping developing safe and effective new therapies and vaccines. These solutions may be […]
Thelancet.com: June 11, 2012. Citicoline is approved in some countries for the treatment of acute ischaemic stroke. The drug has shown some evidence of efficacy in a pooled analysis. We sought to confirm the efficacy of citicoline in a larger trial. Methods We undertook a randomised, placebo-controlled, sequential trial in patients with moderate-to-severe acute ischaemic […]
Archinte.jamanetwork.com: June 4, 2012. Nearly 100 years have passed since a Dutch merchant first astonished Dr Karel Wenckebach with the ability to terminate episodes of atrial fibrillation (AF) through self-medication with quinine.1 Following this initial account of chemical cardioversion, maintenance of sinus rhythm gradually emerged as the preferred but unproven approach to the management of AF. […]
Circ.ahajournals.org: May 9, 2012. Background—Patients with acute coronary syndromes and history of stroke or transient ischemic attack (TIA) have an increased rate of recurrent cardiac events and intracranial hemorrhages. Methods and Results—We evaluated treatment effects of ticagrelor versus clopidogrel in patients with acute coronary syndrome with and without a history of prior stroke or TIA […]
Medicalxpress.com: June 13, 2012. New scientific findings in anticoagulation for stroke prevention are paving the way for updates to the European Society of Cardiology (ESC) Guidelines for the management of atrial fibrillation. Some of these findings were presented during the European Heart Rhythm Association (EHRA) sessions at Cardiostim 2012, 13-16 June, in Nice, France. Cardiostim […]
Thelancet.com: June 13, 2012. Intracerebral haemorrhage accounts for about 10—15% of all strokes and is associated with high mortality and morbidity. No successful phase 3 clinical trials for this disorder have been completed. In the past 6 years, the number of preclinical and clinical studies focused on intracerebral haemorrhage has risen. Important advances have been made […]
