EMA Releases Guideline on Conducting Clinical Trials for Atrial Fibrillation Products

clinicatrials2

Raps.org: By Alexander Gaffney, 8/15/12 The European Medicines Agency (EMA) has released a new guideline for sponsors of products to prevent strokes in patients with non-valvular atrial fibrillation (AF). EMA notes the guideline fills a void left by other guidance documents on antiarrhythmics used to prevent AF, which do not address stroke prevention and systemic embolic events […]

Alliance for Aging Research Releases New Atrial Fibrillation Consensus and Survey; Results Show Less than 50% of Physicians Use Stroke Risk Assessment Tools Regularly

Expert Consensus Statement Recommends Process for Assessing Stroke and Bleeding Risk for Appropriate Anticoagulant Use Clotcare.com: 7/19/12 WASHINGTON, DC (July 19, 2012) – The Alliance for Aging Research (Alliance) announced the release of a new consensus statementwritten by leading experts in the area of stroke prevention in atrial fibrillation (A Fib). The consensus development was spearheaded by the Atrial […]

Haemorrhagic strokes in pregnancy and puerperium

mombaby

http://onlinelibrary.wiley.com. 8/1/12/ There is an increased risk of strokes in pregnancy and puerperium. Intracranial haemorrhage is the rarer of the two stroke subtypes but carries a greater morbidity and mortality for both the mother and the child. This review highlights the causes of pregnancy-related intracranial haemorrhage and its management. The incidence varies from region to region […]

Red Meat Consumption and Risk of Stroke

Stroke.ahajournals.org:  July 31, 2012 Background and Purpose—Prospective studies of red meat consumption and risk of stroke have provided inconsistent results. We performed a meta-analysis to summarize the evidence regarding the effects of red meat (fresh, processed, and total) consumption on stroke risk. Methods—Studies were identified by searching the PubMed database through May 26, 2012, and by […]

Incidence of New Diffusion-Weighted Imaging Lesions Outside the Area of Initial Hypoperfusion Within 1 Week After Acute Ischemic Stroke

Stroke.ahajournals.org: July 31, 2012 Background and Purpose—New diffusion-weighted imaging (DWI) lesions are common in patients with acute ischemic stroke. The pathophysiology of these new lesions is unclear. We differentiated new DWI lesions outside the area of initial hypoperfusion from those confined to the area of initial hypoperfusion. Methods—Patients with acute stroke underwent 3 MRI examinations: on […]

QuickStats: Rate* of Hospitalization for Stroke, by Sex and Age Group — National Hospital Discharge Survey, United States, 2010

Cdc.gov: July 27, 2012 * Per 10,000 population. Hospitalization for stroke (cerebrovascular disease) is defined as a first-listed diagnosis on the medical record of 430–438, as coded according to the International Classification of Diseases, 9th Revision, Clinical Modification. This includes hospitalizations for acute strokes, transient ischemic attack, and for late effects of stroke. Rates were calculated using […]

Shift work and vascular events: systematic review and meta-analysis

Bmj.com: July 26, 2012 To synthesise the association of shift work with major vascular events as reported in the literature. Data sources Systematic searches of major bibliographic databases, contact with experts in the field, and review of reference lists of primary articles, review papers, and guidelines. Study selection Observational studies that reported risk ratios for vascular morbidity, vascular […]

Novel incentive-based approaches to adherence

Ctj.sagepub.com: July 30, 2012. Background Adherence to medications for chronic conditions is often very low, limiting the benefit to patients, even when the medications are effective and have favorable side effect profiles. Purpose This article reviews some of the prior work on treatment adherence, introduces novel concepts from behavioral economics that can be used to design interventions to […]

Lung Function as a Risk Factor for Subarachnoid Hemorrhage

brain

Stroke.ahajournals.org: August 7, 2012 Background and Purpose—The etiology of subarachnoid hemorrhage (SAH) is poorly understood. Reduced lung function, expressed as low forced expiratory volume in 1 second (FEV1) and low forced vital capacity (FVC), is a predictor of cardiovascular disease, but whether reduced lung function is a risk factor for SAH is not known. The association […]

Increased left anterior insular and inferior prefrontal activity in post-stroke mania

heart

Biomedcentral.com: August 6, 2012 Post-stroke mania is an infrequent complication after stroke, and the mechanisms underlying this disorder remain unclear. Although a contralesional release phenomenon has been implicated in post-stroke mania, empirical findings are lacking. Case presentation we preset a case report of post stroke mania. Single photon emission tomography (SPECT) was performed twice, during the […]

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