News
Friday, August 10th, 2012
Stroke.ahajournals.org: 8/6/12 Perfusion imaging has the potential to select patients most likely to respond to thrombolysis. We tested the correspondence of computed tomography perfusion (CTP)-derived mismatch with contemporaneous perfusion-diffusion magnetic resonance imaging (MRI). Methods—Acute ischemic stroke patients 3 to 6 hours after onset had CTP and perfusion-diffusion MRI within 1 hour, before thrombolysis. Relative cerebral […]
News
Friday, August 10th, 2012
stroke.ahajournals.org: August 2, 2012 The purpose of this study was to provide a simple and practical clinical classification for the etiology of intracerebral hemorrhage (ICH). Methods—We performed a retrospective chart review of consecutive patients with ICH treated at the Helsinki University Central Hospital, January 2005 to March 2010 (n=1013). We classified ICH etiology by predefined […]
News
Friday, August 10th, 2012
Onlinelibrary.wiley.com: AUG 1, 2012 Silent brain infarction is a cerebral ischaemic event evident on brain imaging without any clinical symptom. Silent brain infarction is often detected in apparently healthy, elderly people and in different selected patient groups as well. Lately, several studies were carried out in order to identify the clinical conditions leading to silent brain […]
Clinical Trials
Friday, August 10th, 2012
American Medical Association: August 8, 2012 Knowing the complete results of all conducted studies on a question of interest is important to avoid publication and selective outcome reporting biases1 and to obtain a reliable picture of the evidence. However, in many types of research, the problem of selectively missing information does not pertain only to studies that […]
Clinical Trials
Friday, August 10th, 2012
American Heart Association: 8/7/12 Although there is strong evidence on the beneficial effects of virtual reality (VR)-based rehabilitation, it is not yet well understood how the different aspects of these systems affect recovery. Consequently, we do not exactly know what features of VR neurorehabilitation systems are decisive in conveying their beneficial effects. Methods—To specifically address this […]
Clinical Trials
Friday, August 10th, 2012
Onlinelibrary.wiley.com: AUG 7, 2012 Dual antiplatelet therapy with clopidogrel and aspirin reduces the presence and number of microembolic signals in patients with large artery disease. However, whether it is effective in patients with intracranial disease alone remains uncertain. We performed a subgroup analysis of the The CLopidogrel plus Aspirin for Infarction Reduction (CLAIR in acute stroke […]
Clinical Trials
Friday, August 10th, 2012
Trialsjournal.com: August 6, 2012 Selection of appropriate outcomes or domains is crucial when designing clinical trials to compare directly the effects of different interventions in ways that minimise bias. If the findings are to influence policy and practice then the chosen outcomes need to be relevant and important to key stakeholders including patients and the public, […]
Clinical Trials
Friday, August 10th, 2012
The Society for Clinical Trials: August 3, 2012 Background Traditional calculations of sample size do not formally incorporate uncertainty about the likely effect size. Use of a normal prior to express that uncertainty, as recently recommended, can lead to power that does not approach 1 as the sample size approaches infinity. Purpose To provide approaches for calculating sample […]
Therapies
Friday, August 10th, 2012
American College of Cardiology Foundation: August 9, 2012 This analysis aimed to evaluate the association of statin exposure and incident diabetes, and subsequent outcomes in the general population. Background Cardiovascular events as consequences of atherosclerosis and diabetes are reduced by statins. However, statins are associated with excessive risk of diabetes occurrence according to clinical trial analyses. From […]
Therapies
Friday, August 10th, 2012
Fda.gov: Aug. 8, 2012 The U.S. Food and Drug Administration today approved changes to the labeling for the Stryker Wingspan Stent System, including the indications for use. These changes, which the FDA outlined in a safety communication also issued today, specify a more limited group of patients who may benefit from the system. In addition, the safety communication […]
