Hybrid Epicardial-Endocardial Ablation Using a Pericardioscopic Technique for Treatment of Atrial Fibrillation

Heartrhythmjournal.com/: 9/3/12 Catheter ablation is an effective treatment for medically refractory, disabling atrial fibrillation (AF). Ablation success may be limited in patients with persistent or long-standing persistent AF. A pericardioscopic, hybrid epicardial-endocardial technique for AF ablation may be a preferred approach for such patients. Limited data are available using such an approach. Methods A cohort of […]

Type 2 Diabetes Mellitus and Risk of Incident Atrial Fibrillation in Women ONLINE FIRST

Content.onlinejacc.org: 9/1/12 The purpose of this study was to assess whether changes of major atrial fibrillation (AF) risk factors and/or intercurrent cardiovascular events could explain the relationship between type 2 diabetes mellitus (T2D) and incident AF. Background  Previous studies found an increased risk of incident AF among individuals with T2D, but few, if any, of these studies […]

Atrial Fibrillation and the Risk of Ischemic Stroke

Does It Still Matter in Patients With a CHA2DS2-VASc Score of 0 or 1? Sstroke.ahajournals.org: August 7, 2012 Atrial fibrillation (AF) is an independent risk factor for stroke. Recent studies have demonstrated that the CHA2DS2-VASc scheme is useful for selecting patients who are truly at low risk. The goal of the present study was to compare […]

Silent Stroke — Not Listened to Rather Than Silent

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The prevalence of silent brain infarcts varies from 8% to 28% in the general elderly population. Silent brain infarcts are associated with increased risk of subsequent stroke and cognitive dysfunction. By definition, silent strokes lack clinically overt stroke-like symptoms and fail to come to clinical attention; however, impaired recall of symptoms may be a potential […]

Long-Term Rate of Change in Memory Functioning Before and After Stroke Onset

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Stroke.ahajournals.org: August 30, 2012 Background and Purpose—Memory impairment is a predictor and a consequence of stroke, but memory decline is common even in healthy elderly individuals. We compared the long-term trajectory of memory functioning before and after stroke with memory change in stroke-free elderly individuals. Methods—Health and Retirement Study participants aged 50 years and older (n=17 […]

30-Day Risk-Standardized Mortality and Readmission Rates After Ischemic Stroke in Critical Access Hospitals

Stroke.ahajournals.org: August 30, 2012 Background and Purpose—The critical access hospital (CAH) designation was established to provide rural residents with local access to emergency and inpatient care. CAHs, however, have poorer short-term outcomes for pneumonia, heart failure, and myocardial infarction compared with other hospitals. We assessed whether 30-day risk-standardized mortality rates (RSMRs) and risk-standardized readmission rates (RSRRs) […]

Educational History Is an Independent Predictor of Cognitive Deficits and Long-Term Survival in Postacute Patients With Mild to Moderate Ischemic Stroke

Stroke.ahajournals.org: August 30, 2012 Background and Purpose—Poststroke cognitive decline and white matter lesions (WML) are related to poor poststroke survival. Whether cognitive reserve as reflected by educational history associates with cognitive decline, recurrent strokes, and poststroke mortality independent of WML is not known. Methods—A total of 486 consecutive acute mild/moderate ischemic stroke patients subjected to comprehensive […]

Impact of a Pharmacist-Led Warfarin Self-Management Program on Quality of Life and Anticoagulation Control: A Randomized Trial

Onlinelibrary.wiley.com: 8/24/12 Study Objective To evaluate the impact of a pharmacist-led warfarin patient self-management program on quality of life and anticoagulation control compared with management in a physician-led specialized anticoagulation clinic. Design Prospective, randomized, controlled, open-label trial. Setting Tertiary care academic medical center. Patients A total of 114 patients aged 18–75 years who were followed at […]

MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study

Thelancet.com: September 4, 2012 Whether endovascular stroke treatment improves clinical outcomes is unclear because of the paucity of data from randomised placebo-controlled trials. We aimed to establish whether MRI can be used to identify patients who are most likely to benefit from endovascular reperfusion. Methods In this prospective cohort study we consecutively enrolled patients scheduled to […]

Dramatic Recovery in Acute Ischemic Stroke Is Associated With Arterial Recanalization Grade and Speed

Stroke.ahajournals.org: August 30, 2012 Background and Purpose—Dramatic recovery (DR) is a predictor of stroke outcome among others. However, after successful recanalization, systematic favorable outcome is not the rule. We sought to analyze the impact of recanalization on DR in patients with acute ischemic stroke eligible for any revascularization strategies (either intravenous or endovascular). Methods—We analyzed data […]

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