Therapies
Thursday, October 11th, 2012
Ingentaconnect.com: 10/1/12 Background Oral anticoagulants substantially reduce the risk of stroke in atrial fibrillation but are underutilised in current practice. Aim To measure the distribution of stroke risk in patients with atrial fibrillation (using the CHADS2 and CHA2DS2-VASc scores) and changes in oral anticoagulant use during 2007-2010. Design and setting Longitudinal series of cross-sectional survey in […]
Therapies
Thursday, October 11th, 2012
Content.onlinejacc.org: 10/1/12 Since the first reports of ablation therapy being used to treat atrial fibrillation, the field has exploded with studies, new techniques, and new technologies. It is no wonder that such fervor is associated with this topic. Our medical options to maintain sinus rhythm have been generally poorly effective, riddled with side effects, and […]
News
Thursday, October 11th, 2012
Neurology.org: 10/10/12 Objectives: We describe temporal trends in stroke incidence stratified by age from our population-based stroke epidemiology study. We hypothesized that stroke incidence in younger adults (age 20–54) increased over time, most notably between 1999 and 2005. Methods: The Greater Cincinnati/Northern Kentucky region includes an estimated population of 1.3 million. Strokes were ascertained in the population […]
News
Thursday, October 11th, 2012
Neurology.org: 10/9/12 Objective: Intake of fruits and vegetables and levels of serum carotenoids have been associated with decreased risk of stroke, but the results have been inconsistent. The aim of the present study was to examine whether serum concentrations of major carotenoids, α-tocopherol and retinol, are related to any stroke and ischemic stroke in men. Methods: The […]
News
Thursday, October 11th, 2012
Plosone.org: 10/8/12 Background and Purpose Major depressive disorder (MDD) is characterized by recurrent depressive episodes and one of the treatment choices is antidepressants. Patients with MDD are at greater risk of developing major metabolic diseases that may in turn lead to stroke. Moreover, both depressive symptoms and taking antidepressant medications are associated with higher risk […]
News
Thursday, October 11th, 2012
Thelancet.com: 10/5/12 Background Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for […]
News
Thursday, October 11th, 2012
Stroke.ahajournals.org: 10/4/12 Background and Purpose—The contribution of genetics to stroke risk, and whether this differs for different stroke subtypes, remains uncertain. Genomewide complex trait analysis allows heritability to be assessed from genomewide association study (GWAS) data. Previous candidate gene studies have identified many associations with stoke but whether these are important requires replication in large independent […]
News
Friday, October 5th, 2012
Western diet tied to health problems in young rats after just 2 months, study finds. Healthfinder.gov: 10/3/12 WEDNESDAY, Oct. 3 (HealthDay News) — People who eat a so-called “Western diet,” which is high in fat, salt and sugar, are at significantly greater risk for stroke or premature death, according to a new study involving rats. Researchers […]
News
Friday, October 5th, 2012
Nature.com: October 3, 2012 Sex differences in stroke are observed across epidemiologic studies, pathophysiology, treatments, and outcomes. These sex differences have profound implications for effective prevention and treatment and are the focus of this review. Epidemiologic studies reveal a clear age-by-sex interaction in stroke prevalence, incidence, and mortality. While premenopausal women experience fewer strokes than men […]
News
Friday, October 5th, 2012
Stroke.ahajournals.org: October 2, 2012 Little is known about the comparability of stroke subtype mortality across states. We conducted a cross- sectional descriptive study to examine state differences in the reporting of “unspecified stroke” on death certificates in the United States. Methods—The number of deaths from different subtypes of stroke in each state for the years 2007 […]
