Smoking clouds the brain after stroke

Strokecongress.ca:  October 2, 2012 Memory, thinking, decision-making affected by tobacco use Calgary- – A study of stroke patients from Southern Ontario found those who smoke have more difficulty with problem-solving and decision-making than non-smokers. The study, presented today at the Canadian Stroke Congress, tested mental abilities of 76 patients, including 12 smokers, with an average age […]

Stroke genetics: prospects for personalised medicine

Biomedcentral.com: 9/27/12 Epidemiological evidence supports a genetic predisposition to stroke. Recent advances, primarily using the genome wide association study approach, are transforming what we know about the genetics of multifactorial stroke and are identifying novel stroke genes. Current findings are consistent with different stroke subtypes having different genetic architecture. These discoveries may identify novel pathways involved […]

Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis

Neurology.org: October 3, 2012 This study aims to evaluate protective effects of brief repetitive bilateral arm ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic atherosclerotic intracranial arterial stenosis (IAS). Methods: A total of 68 consecutive cases with symptomatic IAS, diagnosed by imaging, were enrolled in this prospective and randomized study. All patients received standard medical […]

Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised controlled trial

Thelancet.com: October 22, 012 The Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial showed that apixaban is better than warfarin at prevention of stroke or systemic embolism, causes less bleeding, and results in lower mortality. We assessed in this trial’s participants how results differed according to patients’ CHADS2, CHA2DS2VASc, and […]

Colchicine for Prevention of Early Atrial Fibrillation Recurrence After Pulmonary Vein Isolation

Content.onlinejacc.org:  October 2012 A Randomized Controlled Study The purpose of the present study was to test the potential of colchicine, an agent with potent anti-inflammatory action, to reduce atrial fibrillation (AF) recurrence after pulmonary vein isolation in patients with paroxysmal AF. Background  Proinflammatory processes induced by AF ablation therapy have been implicated in postablation arrhythmia recurrence. Methods  Patients […]

Does the sliding dichotomy result in higher powered clinical trials for stroke and traumatic brain injury research?

Ctj.sagepub.com: October 1, 2012 Recent research has proposed a new method for defining a favorable outcome in traumatic brain injury and stroke research. Purpose This new method is called the sliding dichotomy, and it is suggested as a potential solution to the problem of underpowered clinical trials. Methods We present a brief simulation study and graphical comparison of […]

Variation in Warfarin Dose Adjustment Practice is Responsible for Differences in the Quality of Anticoagulation Control between Centers and Countries: An Analysis of Patients Receiving Warfarin in the RE-LY Trial

Circ.ahajournals.org: October 1, 2012 The outcome of atrial fibrillation (AF) patients on warfarin partially depends on maintaining adequate time in therapeutic INR range (TTR). Large differences in TTR have been reported between centers and countries. The association between warfarin dosing practice, TTR, and clinical outcomes was evaluated in RE-LY trial patients receiving warfarin. Methods and Results—RE-LY […]

Stent-Based Thrombectomy Versus Intravenous Tissue Plasminogen Activator in Patients With Acute Middle Cerebral Artery Occlusion

Stroke.ahajournals.org: October 2, 2012 Our goal was to compare outcomes of patients with proximal middle cerebral artery occlusions treated with intravenous tissue plasminogen activator (tPA) with those of patients treated with stent-based thrombectomy (SBT). Methods—Patients with proximal middle cerebral artery occlusions included in our prospective stroke registry were identified. Patients presenting with moderate to severe stroke […]

Electromechanical and Robot-Assisted Arm Training After Stroke

Stroke.ahajournals.org: October 2, 2012, More than two thirds of all patients after stroke have difficulties with reduced arm function. Electromechanical and robot-assisted arm training devices are used in rehabilitation and might help to improve arm function after stroke. Our systematic review examined the effectiveness of electromechanical and robot-assisted arm training for improving generic activities of daily […]

Robots uncover stroke disabilities and improve care

Heartandstroke.com: October 1, 2012 CALGARY – When it comes to stroke rehabilitation, it takes a dedicated team to help a person regain as much independence as possible: physicians, nurses, physiotherapists, occupational therapists, speech-language pathologists, recreation therapists, caregivers and others. Now, a University of Calgary research team had added a robot to help identify and customize post-stroke […]

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