Atrial Fibrillation
Sunday, December 16th, 2012
American Journal of Cardiology: 12/15/12 Warfarin decreases risk of stroke for patients with atrial fibrillation (AF) dependent on percent time in the therapeutic range (TTR) with an international normalized ratio (INR) of 2 to 3. We hypothesized that gender differences in ischemic stroke risk are related to TTR. From the AFFIRM database of 4,060 patients with […]
Clinical Trials
Sunday, December 16th, 2012
Wiley: 12/13/12 Objective: Very low cerebral blood volume (VLCBV), diffusion and hypoperfusion lesion volumes have been proposed as predictors of hemorrhagic transformation following stroke thrombolysis. We aimed to compare these parameters, validate VLCBV in an independent cohort using DEFUSE study data and investigate the interaction of VLCBV with regional reperfusion. Methods: The EPITHET and DEFUSE studies […]
Clinical Trials
Sunday, December 16th, 2012
AHA: December 11, 2012 Background and Purpose—History of stroke and transient ischemic attack (TIA) are documented risk factors for subsequent stroke and all-cause mortality. Recent reports suggest increased risk among those reporting stroke symptoms absent stroke or TIA. However, the relative magnitude of increased stroke risk has not been described across the symptomatic spectrum: (1) […]
Clinical Trials
Sunday, December 16th, 2012
Radiology: 12/11/12 Purpose: To compare safety and utility of intraarterial revascularization with use of stents to no revascularization in patients who either failed to respond to intravenous thrombolysis (IVT) or have contraindications to IVT. Materials and Methods: The case-control study was approved by local ethics committees; all patients signed informed consent. One hundred thirty-one patients (74 men; mean […]
Clinical Trials
Sunday, December 16th, 2012
AHA: December 11, 2012, Background and Purpose—The reliability of hematoma volume (HV) measurement using the ABC/2 method in multicenter clinical trials is unknown. We determined the accuracy of ABC/2 method as an on-site test in comparison with the gold standard central HV-assessment and semiautomatic HV-assessment. Method—We analyzed data from an acute intracerebral hemorrhage multicenter clinical trial. […]
Clinical Trials
Sunday, December 16th, 2012
AHA: 12/6/12 Background and Purpose—Communication between hospitals and primary care physicians is essential for the continuity of care for patients being transferred from hospital to ambulatory care. Patients are often discharged from hospital on medication regimes different from those used before hospital admission. The aim of the study was to evaluate the adherence to hospital discharge […]
Therapies
Sunday, December 16th, 2012
J NeuroIntervent Surg: 12/12/12 Background Intra-arterial therapy (IAT) is increasingly used to treat patients with acute stroke with large vessel occlusions. There are minimal data and guidelines for treatment indications and performance standards. We aimed to gain a better understanding of real-world practice patterns for IAT. Methods An internet-based survey was launched to address six specific areas of […]
Therapies
Sunday, December 16th, 2012
Nature Reviews Neurology: 12/11/12 A combination of aerobic and resistance training in patients who have experienced a stroke is associated with improvements in cognitive function, according to a recent study. In 41 patients with poststroke motor impairments who were assigned to a 6-month exercise programme, training was associated with significant improvement in cognition and reduction in […]
Therapies
Sunday, December 16th, 2012
Wiley: 12/11/12 Background Warfarin-associated intracerebral haemorrhage carries poor outcome due to rapid haemorrhage growth. Reversal of warfarin anticoagulation with prothrombin complex concentrate has been implemented as an acute treatment option for these subjects. Aim We investigated whether survival of subjects with warfarin-associated intracerebral haemorrhage had improved after implementation of reversal of warfarin anticoagulation with prothrombin complex […]
Therapies
Sunday, December 16th, 2012
Wiley: 12/11/12 Patients who were treated with and refused t-PA at our stroke center were identified retrospectively. Demographics, clinical presentation, and outcome measures were collected and compared. Clinical outcome was defined as excellent (mRS: 0–1), good (mRS: 0–2), and poor (mRS: 3–6). Results Over 7·5 years, 30 (4·2%) patients refused t-PA. There were no demographic differences […]
