Treatment Targets in Atrial Fibrillation

“Is Feeling Better Good Enough?”⁎⁎ Clinical Research: January 2013 Atrial fibrillation (AF) is the most common sustained arrhythmia necessitating medical therapy. The majority of AF patients have associated cardiovascular comorbidities that increase the risk of negative cardiovascular outcomes, including excess morbidity, hospitalizations, and mortality ((1),2). Data assessing a disease management strategy of rate versus rhythm control […]

Stepwise Screening of Atrial Fibrillation in a 75-Year Old Population: Implications for Stroke Prevention

CIRCULATIONAHA: January 23, 2013 Background—Atrial fibrillation (AF) is a frequent source of cardiac emboli in patients with ischemic stroke. AF may be asymptomatic and therefore undiagnosed. Screening for silent AF seems suitable in risk populations, little is however known on the yield and cost-effectiveness of such screening. Methods and Results—All inhabitants in the municipality of Halmstad, […]

Atrial fibrillation increases risk of kidney failure in people with CKD

News-medical: January 18, 2013 Many people who suffer from chronic kidney disease progressively lose their kidney function over time and eventually develop a condition called end-stage renal disease – the complete failure of the kidneys – placing them in need of lifelong dialysis or akidney transplant. Now researchers at the University of California, San Francisco (UCSF) and the […]

Quality of Life and Functional Capacity in Patients With Atrial Fibrillation and Congestive Heart Failure

JACC: January 2013 Objectives  This study sought to assess the impact of rhythm- versus rate-control treatment strategies and of underlying rhythm on quality of life and functional capacity in patients with atrial fibrillation (AF) and congestive heart failure (CHF). Background  Although intention-to-treat and efficacy analyses have demonstrated similar cardiovascular outcomes in patients with AF and CHF randomized to […]

Shoulder taping reduces injury and pain in stroke patients Randomized controlled trial

Neurology: January 23, 2013 Objectives: We aimed to study the effectiveness of shoulder taping and conventional treatment vs sham taping and conventional treatment in prevention of shoulder injuries in patients with acute stroke. Methods: This study was a multicenter, interventional, prospective, randomized, outcome-blinded trial (PROBE design). All first-ever stroke patients were included within 48 hours of stroke onset […]

Real-time Validation of Transcranial Doppler Criteria in Assessing Recanalization During Intra-arterial Procedures for Acute Ischemic Stroke An International, Multicenter Study

STROKEAHA: January 10, 2013 Background and Purpose—We sought to evaluate the diagnostic accuracy of ultrasound criteria for recanalization during real-time transcranial Doppler monitoring of intra-arterial reperfusion procedures in acute ischemic stroke patients in an international, multicenter study. Methods—Consecutive acute ischemic stroke patients with proximal intracranial occlusions underwent intra-arterial reperfusion procedures with simultaneous real-time transcranial Doppler monitoring […]

Smoking-Thrombolysis Paradox

STROKEAHA: January 3, 2013 Background and Purpose—The so-called smoking-thrombolysis paradox of an improved outcome after thrombolysis was first described in smokers with myocardial infarction. We investigated whether reperfusion rates and clinical outcome differ between smokers and nonsmokers with ischemic stroke after intravenous tissue plasminogen activator. Methods—Consecutive acute ischemic stroke patients, who had magnetic resonance imaging before […]

Pilot Randomized Trial of Outpatient Cardiac Monitoring After Cryptogenic Stroke

STROKEAHA: November 27, 2012 Background and Purpose—Observational studies indicate that outpatient cardiac monitoring detects previously undiagnosed atrial fibrillation (AF) in 5% to 20% of patients with recent stroke. However, it remains unknown whether the yield of monitoring exceeds that of routine clinical follow-up. Methods—In a pilot trial, we randomly assigned 40 patients with cryptogenic ischemic stroke […]

Oxygen Therapy Spurs Recovery in Some Stroke Patients

Healthday: By Amanda Gardner, HealthDay Reporter – January 26, 2013 Study found certain survivors gained lost skills months, years after their attack TUESDAY, Jan. 22 (HealthDay News) — Researchers in Israel report that they harnessed the same type of therapy that helps scuba divers recover from the bends to spur recovery in stroke survivors. The treatment, known as […]

Induction of Cooling With a Passive Head and Neck Cooling Device Effects on Brain Temperature After Stroke

STROKEAHA: January 22, 2013 Background and Purpose—Therapeutic hypothermia improves clinical outcome after cardiac arrest and appears beneficial in other cerebrovascular diseases. We conducted this study to investigate the relationship between surface head/neck cooling and brain temperature. Methods—Prospective observational study enrolling consecutive patients with severe ischemic or hemorrhagic stroke undergoing intracranial pressure (ICP) and brain temperature monitoring. […]

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