Practice Guideline: Methodology

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Ahajournals: December 10, 2012 The American College of Cardiology Foundation (ACCF) and the American Heart Association (AHA) have jointly engaged in the development of clinical practice guidelines (CPGs) for nearly 3 decades, based on the shared vision of their responsibility to provide guidance to cardiovascular healthcare professionals and the patients they serve by translating the best […]

2012 ACCF/ AHA/ ACP/ AATS/ PCNA/ SCAI/ STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease

JACC: 11/20/12 The  medical profession should play a central role in evaluating the evidence related to drugs, devices, and procedures for the detection, management, and prevention of disease. When properly applied, expert analysis of available data on the benefits and risks of these therapies and procedures can improve the quality of care, optimize patient outcomes, and favorably […]

Advances in Stroke

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Stroke.ahajournals.org: January 15, 2013 The field of stroke genetics continues to make substantive advances. Large-scale partnerships have led to meta-analyses in ischemic and hemorrhagic stroke, which are yielding reproducible genetic risk factors. Most ischemic stroke risk factors seem to be specific to type, for example, large-vessel stroke. Progress is being made in understanding the pathophysiology of […]

A quantitative systematic review of domain-specific cognitive impairment in lacunar stroke

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Neurology.org: January 15, 2013 Objective: To quantitatively characterize domain-specific cognition in individuals with symptomatic lacunar stroke in a systematic review. Methods: Systematic searches of MEDLINE and EMBASE were conducted. Inclusion criteria were all articles published prior to December 2011 evaluating domain-specific cognitive status in individuals with a symptomatic lacunar infarct. Data extraction identified cognitive domains with reported impairment […]

Depressed Stroke Survivors May Face Triple the Risk of Death

Aan.com: JANUARY 11, 2013 AN DIEGO – People who are depressed after a stroke may have a tripled risk of dying early and four times the risk of death from stroke than people who have not experienced a stroke or depression, according to a study released today that will be presented at the American Academy of Neurology’s 65th Annual […]

Comparison of Ischemic Stroke Outcomes and Patient and Hospital Characteristics by Race/Ethnicity and Socioeconomic Status

STROKEAHA: January 10, 2013 Background and Purpose—Current literature provides mixed evidence on disparities by race/ethnicity and socioeconomic status in discharge outcomes after hospitalization for acute ischemic stroke. Using comprehensive data from 8 states, we sought to compare inpatient mortality and length of stay by race/ethnicity and socioeconomic status. Methods—We examined all 2007 hospitalizations for acute ischemic […]

Stroke disability and rehabilitation of stroke: World Health Organization perspective

Journal of Stroke:  DEC 24, 2012 Stroke is a leading cause of acquired disability in adults. If secular trends continue it is estimated that there will be 23 million first ever strokes and 7·8 million stroke deaths in 2030 [1]. In 2008, out of 57 million global deaths, 17 million were due to cardiovascular diseases [2]. Stroke […]

Atrial Remodeling Role in Atrial Fibrillation Ablation

Jafib: January 13th, 2013 There have been considerable advances in understanding the relationship of atrial fibrillation (AF) and atrial remodelling suggesting that remodelling states have a significant impact on treatment results. Therefore, we reviewed the literature about the role of atrial remodelling in AF treatment, focussing on AF ablation. Atrial fibrillatory activity, dominant frequencies (DF), complex fractionated atrial […]

Incident Atrial Fibrillation and Risk of End-Stage Renal Disease in Adults with Chronic Kidney Disease

CIRCULATIONAHA: December 28, 2012 Background—Atrial fibrillation (AF) frequently occurs in patients with chronic kidney disease (CKD). However, the long-term impact of development of AF on the risk of adverse renal outcomes in patients with CKD is unknown. In this study, we determined the association between incident AF and risk of end-stage renal disease (ESRD) among adults […]

Temporal Trends in Ischemic Stroke and Anticoagulation Therapy Among Medicare Patients With Atrial Fibrillation

A 15-Year Perspective (1992-2007) JAMA: 12/24/12 A trial fibrillation (AF) is an independent, modifiable risk factor for ischemic stroke1 and independently associated with increased mortality.2 Nonvalvular AF is associated with a nearly 5-fold higher risk of ischemic stroke; this risk progressively increases with age.3 In a meta-analysis involving 29 clinical studies and 28 044 patients, judicious antithrombotic therapy with […]

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