Patient-Reported Measures Provide Unique Insights Into Motor Function After Stroke

STROKEAHA: February 19, 2013 Background and Purpose—Patient-reported outcome measures have been found useful in many disciplines but have received limited evaluation after stroke. The current study investigated the relationship that patient-reported measures have with standard impairment and disability scales after stroke. Methods—Patients with motor deficits after stroke were scored on standard assessments including the National Institutes […]

Changing Demographics at a Comprehensive Stroke Center Amidst the Rise in Primary Stroke Centers

STROKEAHA: February 14, 2013 Background—The creation of The Joint Commission primary stroke centers (PSCs) has increased access to acute stroke care in metropolitan areas. We hypothesized that the rise in PSCs in the Houston area was associated with demographic changes and decreased trial enrollment at our comprehensive stroke center. Methods—Consecutive admissions to the UT Houston stroke […]

Rate Control Efficacy in Permanent Atrial Fibrillation: Successful and Failed Strict Rate Control Against a Background of Lenient Rate Control

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JACC: February 19, 2013 Objectives  This study sought to investigate differences in outcome between patients treated with successful strict, failed strict, and lenient rate control. Background  The RACE II (Rate Control Efficacy in Permanent Atrial Fibrillation) study showed no difference in outcome between lenient and strict rate control in patients with permanent atrial fibrillation (AF). However, in the […]

Relationship of Sudden Cardiac Death to New-Onset Atrial Fibrillation in Hypertensive Patients with Left Ventricular Hypertrophy

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CIRCEP: February 12, 2013 Background-Prevalent atrial fibrillation (AF) is associated a higher sudden cardiac death (SCD) rate in some populations and incident AF predicts increased mortality risk in the general population and after myocardial infarction. However, the relationship of SCD to new-onset AF is unclear. Read more

Panoramic Electrophysiological Mapping But Not Electrogram Morphology Identifies Stable Sources for Human Atrial Fibrillation: Stable AF Rotors and Focal Sources Relate Poorly to Fractionated Electrograms

CIREP: February 7, 2013 Background-The foundation for successful arrhythmia ablation is the mapping of electrical propagation to identify underlying mechanisms. In atrial fibrillation (AF), however, mapping is difficult so that ablation has often targeted electrogram features, with mixed results. We hypothesized that wide-field of view (panoramic) mapping of both atria would identify causal mechanisms for AF […]

A Trial of Imaging Selection and Endovascular Treatment for Ischemic Stroke

NEJM: February 8, 2013 BACKGROUND Whether brain imaging can identify patients who are most likely to benefit from therapies for acute ischemic stroke and whether endovascular thrombectomy improves clinical outcomes in such patients remains unclear. Read more

Lower blood pressure targets safe in reducing risk of recurrent stroke

American Heart Association: February 08, 2013 American Stroke Association Late-Breaking Science Report: Abstract LB 8 – Embargoed until 7 a.m. HT/ noon ET on Friday, Feb. 8, 2013 Study Highlights: Survivors of small-artery strokes who lowered their systolic blood pressure below 130 mm Hg were less likely to suffer a hemorrhagic stroke (bleeding in the brain) […]

Delay in breaking up blood clots means worse stroke outcome

American Heart Association: February 08, 2013 American Stroke Association Late-Breaking Science Report: Abstract LB 9 Embargoed until 7 a.m. HT/ noon ET on Friday, Feb. 8, 2013 Study Highlights: In patients who had endovascular therapy added to intravenous clot-busting drugs to restore blood flow after a stroke within seven hours, every 30-minute delay in breaking up […]

Adding clopidogrel to aspirin therapy reduces risk of second stroke

American Heart Association: February 08, 2013 American Stroke Association Late-Breaking Science Report: Abstract LB 11 Embargoed until 7 a.m. HT/ noon ET on Friday, Feb. 8, 2013 Study Highlights: Adding a second drug to aspirin therapy lowered the risk of a second stroke in the weeks after a clot caused minor stroke or TIA in Chinese […]

Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke

NEJM: February 7, 2013 BACKGROUND Endovascular therapy is increasingly used after the administration of intravenous tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute ischemic stroke, but whether a combined approach is more effective than intravenous t-PA alone is uncertain. Read more

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