Chronic Pain Syndromes After Ischemic Stroke

Ischemic Stroke

​STROKEAHA: April 4, 2013 Background and Purpose—Chronic pain syndromes are reported to be common after stroke, but most previous epidemiological studies have generally included small cohorts of patients with relatively short-term follow-up. In a large cohort with ischemic stroke (Prevention Regimen for Effectively avoiding Second Stroke [PRoFESS] trial), we determined the prevalence, risk factors, and clinical […]

Heritability Estimates Identify a Substantial Genetic Contribution to Risk and Outcome of Intracerebral Hemorrhage

​STROKEAHA: April 4, 2013 Background and Purpose—Previous studies suggest that genetic variation plays a substantial role in occurrence and evolution of intracerebral hemorrhage (ICH). Genetic contribution to disease can be determined by calculating heritability using family-based data, but such an approach is impractical for ICH because of lack of large pedigree-based studies. However, a novel analytic […]

BRAIN Initiative Challenges Researchers to Unlock Mysteries of Human Mind

White House Blog: April 02, 2013 Today at the White House, President Obama unveiled the “BRAIN” Initiative—a bold new research effort to revolutionize our understanding of the human mind and uncover new ways to treat, prevent, and cure brain disorders like Alzheimer’s, schizophrenia, autism, epilepsy, and traumatic brain injury. The BRAIN Initiative — short for Brain Research through Advancing Innovative Neurotechnologies — builds […]

Risk Factors for Intracerebral Hemorrhage

STROKEAHA: March 26, 2013 Background and Purpose—Risk factors for intracerebral hemorrhage (ICH) have been largely identified in case–control studies, with few longitudinal studies available. Methods—Predictors of incident ICH among 27 760 black and white participants from the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort study were assessed. Results—There were 62 incident ICH events during […]

Atrial Fibrillation and Warfarin Use in Haemodialysis Patients: An Individualized Holistic Approach is Important in Stroke Prevention

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Nephrology: March 25, 2013 Abstract Incidence and prevalence of Atrial Fibrillation (AF) is higher in hemodialysis (HD) population than general population. AF is associated with higher morbidity and mortality than sinus rhythm in this population. The purpose of this review is to summarize all available evidence regarding use of warfarin in HD patients with AF […]

Regular Physical Activity and Risk of Atrial Fibrillation: A Systematic Review and Meta-Analysis

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​CIRCEP: March 20, 2013 Background—While previous studies have suggested that competitive athletes have a higher risk of atrial fibrillation (AF) than the general population, limited and inconsistent data are available on the association between regular physical activity (PA) and the risk of AF. Methods and Results—A systematic, comprehensive literature search using MEDLINE, EMBASE, and COCHRANE until […]

Arrhythmia and Electrophysiology

J Am Heart Assoc.: March 18, 2013 Background In the past decade, catheter ablation has become an established therapy for symptomatic atrial fibrillation (AF). Until very recently, few data have been available to guide the clinical community on the outcomes of AF ablation at ≥3 years of follow‐up. We aimed to systematically review the medical literature to […]

Factors that influence awareness and treatment of atrial fibrillation in older adults

QJM: March 14, 2013 Aim: The aims of this study were to investigate the prevalence of atrial fibrillation (AF), treatment rates of AF and the factors underlying awareness and treatment, in a large nationally representative study. Methods: A population sample of people aged 50+, living in the Republic of Ireland, were recruited as part of The Irish longitudinal […]

Gender Matters: Why Afib Is More Fatal for Women

EP Lab Digest: March 4, 2014 In recent years, there have been many revelations about heart disease and how it specifically affects women. Research has shown that women frequently have different symptoms of a heart attack than men, and women are often worse off after a heart attack.1 Not surprisingly, the diagnosis, symptoms, and treatments […]

Efficacy of Coupling Inhibitory and Facilitatory Repetitive Transcranial Magnetic Stimulation to Enhance Motor Recovery in Hemiplegic Stroke Patients

​STROKEAHA: March 26, 2013 Background and Purpose—Although there has been extensive research on the effectiveness of repetitive transcranial magnetic stimulation (rTMS) to improve patients’ motor performance after experiencing chronic stroke, explicit findings on the coupling of different rTMS protocols are meager. We designed this sham-controlled randomized study to investigate the potential for a consecutive suppressive-facilitatory TMS […]

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