Therapies
Wednesday, May 29th, 2013
The Lancet Neurology: June 1, 2013 Early recanalisation and an increase in collateral blood supply are predictors of favourable outcome in acute ischaemic stroke. Since individual responses to intravenous treatment with alteplase are heterogeneous, additional intra-arterial thrombolytic and mechanical endovascular treatment is increasingly given. Despite encouraging findings from single-centre studies, data from randomised clinical trials […]
Therapies
Wednesday, May 29th, 2013
The Lancet Neurology: June 1, 2013 Thrombolysis with alteplase administered within a narrow therapeutic window provides an effective therapy for acute ischaemic stroke. However, mainly because of prehospital delay, patients often arrive too late for treatment, and no more than 1—8% of patients with stroke obtain this treatment. Read more
Therapies
Wednesday, May 29th, 2013
STROKEAHA: May 23, 2013 Background and Purpose—To investigate relationships between the degree of early reperfusion achieved on perfusion-weighted imaging and clinical outcomes in the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution studies. We hypothesized that there would be a strong correlation between the degree of reperfusion achieved and clinical outcomes in target mismatch (TMM) […]
Therapies
Wednesday, May 29th, 2013
International Journal of Stroke: May 22, 2013 Background Low-frequency repetitive transcranial magnetic stimulation of the nonlesional hemisphere combined with occupational therapy significantly improves motor function of the affected upper limb in poststroke hemiparetic patients, but the recovery mechanism remains unclear. Aims To investigate the recovery mechanism using functional magnetic resonance imaging. Read more
Therapies
Wednesday, May 29th, 2013
STROKEAHA: May 16, 2013 Background and Purpose—Use of endovascular coiling for treatment of ruptured and unruptured intracranial aneurysms (IAs) in the elderly is increasing. We performed a meta-analysis of the literature examining clinical and angiographic outcomes for treatment of IAs in the elderly. Methods—We performed a comprehensive review of the literature from 1995 to 2012, reporting […]
News
Wednesday, May 29th, 2013
StrokeAHA: May 22, 2013 Background and Purpose—Stroke is a leading cause of disability, cognitive impairment, and death in the United States and accounts for 1.7% of national health expenditures. Because the population is aging and the risk of stroke more than doubles for each successive decade after the age of 55 years, these costs are anticipated […]
News
Wednesday, May 29th, 2013
CIRCOUTCOMES: May 16, 2013 Background—Little is known as to whether long-term outcomes of acute ischemic stroke (AIS) vary by race/ethnicity. Using the American Heart Association Get With The Guidelines–Stroke registry linked with Medicare claims data set, we examined whether 30-day and 1-year outcomes differed by race/ethnicity among older patients with AIS. Methods and Results—We analyzed 200 […]
News
Wednesday, May 29th, 2013
STROKEAHA: May 16, 2013 Background and Purpose—To determine the interrelationships between baseline Mini-Mental State Examination (MMSE) score and risk of overall dementia, post-recurrent stroke dementia, and dementia without recurrent stroke among patients with a history of stroke. Methods—Prospective cohort study among participants enrolled in the Perindopril Protection Against Recurrent Stroke Study (PROGRESS) for whom baseline MMSE […]
News
Wednesday, May 29th, 2013
STROKEAHA: May 16, 2013 Background and Purpose—Predictive value of the conventional risk factors for stroke attenuates with age. Cognitive impairment has been implicated as a potential predictor for stroke in older subjects. Our aim was to compare the Framingham stroke risk score with cognitive functioning for predicting first-time stroke in a cohort of the oldest old […]
Atrial Fibrillation
Friday, May 17th, 2013
J Am Coll Cardiology: May 21, 2013 Objectives This study sought to determine the risk of ischemic stroke (IS)/thromboembolism (TE) associated with renal impairment and its incremental predictive value over established risk stratification scores (congestive heart failure, hypertension, age ≥75 years, diabetes, previous stroke [CHADS2] and congestive heart failure, hypertension, age ≥75 years, diabetes, previous stroke, […]