AHA Journals – June 6, 2013 Background and Purpose—The American Heart Association developed Life’s Simple 7 (LS7) as a metric defining cardiovascular health. We investigated the association between LS7 and incident stroke in black and white Americans. Methods—The Reasons for Geographic And Racial Differences in Stroke (REGARDS) is a national population-based cohort of 30 239 blacks […]
AHA Journals – June 6, 2013. Background and Purpose—Much recent interest surrounds the use of action observation, which is observing another individual performing a motor task, in stroke rehabilitation, to promote motor recovery by engaging similar brain regions to action execution. This may be especially useful in individuals with limited mobility. Here, we assess how […]
AHA Journals, June 6, 201 Background and Purpose—Research on the relationship between caffeine-containing medicines (CCMs) and the risk of hemorrhagic stroke (HS) is sparse. The aim of this study is to evaluate the association between CCMs and the risk of HS. Methods—We performed a multicenter case–control study in South Korea, from 2002 to 2004. A total […]
The Lancet Neurology, May 31, 2013. Haemorrhagic transformation (HT) of ischaemic infarction occurs when an area of brain infarction is stained with blood products, mainly red blood cells. An abnormally permeable blood—brain barrier resulting from ischaemia of the capillary endothelium allows this extravasation of blood products. HT is part of the natural history of some forms […]
AHA – May 23, 2013 Background and Purpose—The study aimed to assess whether onset headache is an ominous sign in patients with first-ever ischemic stroke. Methods—A large population of ischemic stroke patients was obtained from the Taiwan Stroke Registry. Stroke subtypes were classified by the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria. […]
JACC: June 4, 2013 Most clinicians would like to be able to accurately estimate the risk of adverse outcomes, especially if this information could guide management or treatment decisions to lower the risk for an individual. In the case of atrial fibrillation (AF), the most common cardiac arrhythmia, more accurate prediction of its most feared […]
PLOS One: May 24, 2013 Background A prolonged PR interval is a sign of increased risk of cardiac arrhythmia. Recent genome-wide association studies found that the single-nucleotide polymorphism (SNP) rs3825214 in T-box 5 (TBX5) was positively associated with PR interval, QRS duration, QT interval, and common arrhythmia disorders such as atrial fibrillation (AF) and advanced […]
Eur Heart J: May 22, 2013 The terms compliance, adherence, concordance, and persistence are used to characterize important aspects of medication-taking behaviour. According to the International Society for Pharmacoeconomics and Outcomes Research Medication Compliance and Persistence Work Group, medication compliance (or adherence) is defined as ‘the extent to which a patient acts in accordance with the […]
Stroke: June 1, 2013 Intracerebral hemorrhage (ICH) accounts for 10% to 15% of all strokes. ICH continues to impart a considerable degree of morbidity and mortality, with 30-day mortality ranging from 44% to 50%.1–3 ICH remains a devastating disease, and current treatment options lag far behind those for ischemic stroke. There are no approved therapies, which […]
The Lancet: May 29, 2013 Background Lowering of blood pressure prevents stroke but optimum target levels to prevent recurrent stroke are unknown. We investigated the effects of different blood-pressure targets on the rate of recurrent stroke in patients with recent lacunar stroke. Methods In this randomised open-label trial, eligible patients lived in North America, Latin […]
