STROKEAHA: August 22, 2013 A Systematic Review and Meta-Analysis of 81 Cohorts, Including 3 980 359 Individuals and 42 401 Strokes Background and Purpose—It is currently unknown whether the excess risk of stroke by smoking is the same for women and men. We performed a systematic review and meta-analysis to estimate the effect of smoking on […]
STROKEAHA: August 20, 2013 Background and Purpose—Age-related impairments in cerebral blood flow and cerebrovascular reactivity to carbon dioxide (CVRCO2) are established risk factors for stroke that respond favorably to aerobic training. The present study examined to what extent cerebral hemodynamics are improved when training is sustained throughout the adult lifespan. Methods—Eighty-one healthy males were prospectively assigned […]
Biomedcentral: August 15, 2013 Background Stroke is a time-dependent medical emergency in which early presentation to specialist care reduces death and dependency. Up to 70% of all stroke patients obtain first medical contact from the Emergency Medical Services (EMS). Identifying ‘true stroke’ from an EMS call is challenging, with over 50% of strokes being misclassified. The […]
Neurology: 8/14/13 Objective: To examine temperature in relation to stroke mortality in a multicity time series study in China. Methods: We obtained data on daily temperature and mortality from 8 large cities in China. We used quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on stroke mortality across multiple days, […]
STROKEAHA: August 8, 2013 Background and Purpose—Visit-to-visit variability in blood pressure (vBP) is associated with ischemic stroke. We sought to determine whether such variability has genetic causes and whether genetic variants associated with BP variability are also associated with ischemic stroke. Methods—A Genome Wide Association Study (GWAS) for loci influencing BP variability was undertaken in 3802 […]
JACC: 2013 Objectives This study evaluated whether subclinical episodes of atrial fibrillation (AF) were associated with an increased risk of silent cerebral infarct (SCI) and stroke in diabetic patients younger than 60 years who did not have other clinical evidence of AF and cerebrovascular disease at baseline. Background In type 2 diabetic patients, one-fourth of strokes are […]
JACC: 8/6/13 Primary Goal in the Therapy of Atrial Fibrillation∗ Treatment of atrial fibrillation (AF) involves 3 major strategies: prevention of stroke, maintenance of sinus rhythm, and rate control 1. Stroke is the most dreaded complication of AF, and its prevention is key. Anticoagulation with warfarin and the newer agents dabigatran, rivaroxaban, and apixaban is highly effective […]
Neurology: July 31, 2013 Objective: We determined whether patient characteristics (age, sex, comorbidities), stroke severity, and quality of care explained a proportion of the association between atrial fibrillation (AF) and increased disability and mortality in patients with acute ischemic stroke. Methods: The study included a prospective cohort of consecutive patients admitted with acute ischemic stroke included in […]
Ajconline: July 08, 2013 Estimates and projections of diagnosed incidence and prevalence of atrial fibrillation (AF) in the United States have been highly inconsistent across published studies. Although it is generally acknowledged that AF incidence and prevalence are increasing due to growing numbers of older people in the U.S. population, estimates of the rate of expected […]
Jacc: August 2013 Objectives This study sought to determine whether post-operative neurocognitive dysfunction (POCD) occurs after ablation for atrial fibrillation (AF). Background Ablation for AF is a highly effective strategy; however, the risk of transient ischemic attack and stroke is approximately 0.5% to 1%. In addition, magnetic resonance imaging studies report a 7% to 14% prevalence of silent cerebral […]
