Neurology: 2/7/14 Objective: We aimed to compare quality of life (QOL) in women and men after ischemic stroke or TIA, and to determine the incremental impact of demographic, socioeconomic, clinical, and stroke-specific effects on longitudinal QOL. Methods: We assessed QOL in patients with ischemic stroke or TIA at 3 and 12 months postdischarge in the Adherence eValuation […]
CIRCRESAHA: March 14, 2014 The autonomic nervous system plays an important role in the modulation of cardiac electrophysiology and arrhythmogenesis. Decades of research has contributed to a better understanding of the anatomy and physiology of cardiac autonomic nervous system and provided evidence supporting the relationship of autonomic tone to clinically significant arrhythmias. The mechanisms by which […]
Schattauer.: 3/11/14 Atrial fibrillation (AF) is an independent risk factor for thromboembolism and stroke. Women with AF are at a higher overall risk for thromboembolic stroke when compared to men with AF. Recent evidence suggests that female sex, after adjusting for stroke risk profile and sex differences in utilisation of anticoagulation, is an independent stroke risk […]
AHA – CIRCEP: March 8, 2014 Background—Endogenous sex hormones have been related to cardiovascular outcomes and mortality. We hypothesized that sex hormones are related to atrial fibrillation (AF) in a community-based cohort of middle-aged to older men. Methods and Results—We examined testosterone, estradiol, and dehydroepiandrosterone sulfate [DHEA-S]) in relation to incident AF in men participating in […]
CIRCULATIONAHA: 3/4/14 Atrial fibrillation (AF) is the most common sustained heart rhythm disorder, with an estimated prevalence of 0.4% to 1% in the general population. In addition, AF is responsible for approximately 15% to 20% of ischemic strokes. Device interventions to prevent strokes in patients with AF are nonsurgical procedures to block blood clots (thrombus) from […]
J Am Heart Assoc.: January 21, 2014 New‐Onset Atrial Fibrillation is Associated With Cardiovascular Events Leading to Death in a First Time Myocardial Infarction Population of 89 703 Patients With Long‐Term Follow‐Up: A Nationwide Study Background New‐onset atrial fibrillation (AF) is reported to increase the risk of death in myocardial infarction (MI) patients. However, previous studies have […]
BMJ: 3/20/14 Abstract Introduction Concomitant surgical ablation is a treatment modality for patients with atrial fibrillation (AF) undergoing cardiac surgery, however, its efficacy and clinical outcomes are not well established. The present study is the first cumulative meta-analysis of randomised controlled trials (RCT) on clinical outcomes of surgical ablation versus no ablative treatment in all patients with […]
Wiley: MAR 12, 2014 Background In the interest of prioritizing resources and providing future direction for researchers, a complete overview of the landscape of stroke rehabilitation literature was conducted. Aim We aimed to examine the evolution of stroke rehabilitation randomized controlled trials, with respect to number, sample size, and methodological quality between 1970 and September 2012. […]
STROKEAHA: March 6, 2014 Background and Purpose—Intravenous recombinant tissue-type plasminogen activator (rtPA), despite a risk of early symptomatic intracranial hemorrhage (sICH), is of net clinical benefit to acute stroke patients. We tested if predictive models could identify patients least likely to be harmed by sICH or those who gained no net benefit. Methods—We used the Third […]
JACC in a Flash: 3/1/14 In patients with atrial fibrillation (AF), anticoagulation strategies must be carefully selected—taking into consideration the risk of bleeding and thromboembolic events and the interaction with potential treatments to correct cardiac arrhythmias. Three novel oral anticoagulant (NOAC) drugs have been approved for stroke prevention in these patients over the last few years, […]
