Guidelines
Monday, June 9th, 2014
JAMA: 5/28/14 Importance Little is known regarding the durability of clinical practice guideline recommendations over time. Objective To characterize variations in the durability of class I (“procedure/treatment should be performed/administered”) American College of Cardiology/American Heart Association (ACC/AHA) guideline recommendations. Design, Setting, and Participants Textual analysis by 4 independent reviewers of 11 guidelines published between 1998 and 2007 and revised […]
Guidelines
Monday, June 9th, 2014
AHA: May 20, 2014 Purpose—This scientific statement provides an overview of the evidence on physical activity and exercise recommendations for stroke survivors. Evidence suggests that stroke survivors experience physical deconditioning and lead sedentary lifestyles. Therefore, this updated scientific statement serves as an overall guide for practitioners to gain a better understanding of the benefits of […]
Atrial Fibrillation
Monday, June 9th, 2014
CIRCULATIONAHA: May 19, 2014 Background—Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. The associated morbidity and mortality makes AF a major public health burden. Hospitalizations account for the majority of the economic cost burden associated with AF. The main objective of this study is to examine trends of AF related hospitalizations in the US […]
Atrial Fibrillation
Monday, June 9th, 2014
CIRCEP: May 17, 2014 Background—We classified patients’ atrial fibrillation (AF), assessed its impact on bi-ventricular pacing (BIVP%), and determined if AF classification or BIVP% independently correlate with mortality in Cardiac Resynchronization Therapy Defibrillator (CRT-D) patients. Methods and Results—CRT-D patients were classified as Permanent (daily mean AF burden ≥23 hours), Persistent (≥7 consecutive days of AF ≥23 […]
Atrial Fibrillation
Monday, June 9th, 2014
CIRCEP: 5/15/14 Background—Recent studies reported worse outcomes after atrial fibrillation (AF) ablation in patients with metabolic syndrome (MetS). However, mechanisms of AF recurrence in MetS remain unclear. Method and Results—We performed pulmonary vein isolation and voltage mapping in two hundred thirty-six AF patients (age 61±9.6 y.; persistent AF 64%, MetS 54%). LA low-voltage (LoVo) areas were […]
Atrial Fibrillation
Monday, June 9th, 2014
Wiley: 5/15/14 Background Direct oral anticoagulants (DOAC) are alternatives to the use of vitamin K antagonists (VKA) as oral anticoagulant therapies to prevent stroke in patients with atrial fibrillation. Aims We assembled a representative secondary prevention cohort from four tertiary care stroke centers to identify factors that independently influence therapeutic decision making 1) not to anticoagulate […]
Atrial Fibrillation
Monday, June 9th, 2014
CIRCEP: May 14, 2014 Background—Rapid pulmonary vein (PV) activity has been shown to maintain paroxysmal AF. We evaluated in persistent AF (PsAF) the cycle length (CL) gradient between PVs and the left atrium (LA) in an attempt to identify the subset of patients where PVs play an important role. Methods and Results—97 consecutive patients undergoing first […]
Clinical Trials
Monday, June 9th, 2014
STROKEAHA: May 15, 2014 Background and Purpose—We report on workflow and process-based performance measures and their effect on clinical outcome in Solitaire FR Thrombectomy for Acute Revascularization (STAR), a multicenter, prospective, single-arm study of Solitaire FR thrombectomy in large vessel anterior circulation stroke patients. Methods—Two hundred two patients were enrolled across 14 centers in Europe, Canada, […]
Clinical Trials
Monday, June 9th, 2014
Wiley- International Journal of Stroke: 5/15/14 Rationale Cooling reduced infarct size and improved neurological outcomes in animal studies modeling ischemic stroke, and also improved outcome in randomized clinical trials in patients with hypoxic-ischemic brain injury after cardiac arrest. Cooling awake patients with ischemic stroke has been shown feasible in phase II clinical trials. Primary aim To […]
Clinical Trials
Monday, June 9th, 2014
STROKEAHA: May 13, 2014 Background and Purpose—Subdural hematomas are an important bleeding complication of anticoagulation. We quantify the risk of subdural hematoma associated with anticoagulation with vitamin K antagonists (VKAs) compared with other oral antithrombotic therapies. Methods—Randomized trials were identified from the Cochrane Central Register of Controlled Trials and were included if published since 1980 and […]
