Quality of life after surgical decompression for space-occupying middle cerebral artery infarction: Systematic review

Wiley: 15 JUL 2014 Background and Purpose In patients with space-occupying middle cerebral artery infarction, surgical decompression strongly reduces risk of death and increases the chance of a favorable outcome. This comes at the expense of an increase in the risk of survival with (moderately) severe disability. We assessed quality of life, depression, and caregiver burden […]

Standard-Dose Intravenous Tissue-Type Plasminogen Activator for Stroke Is Better Than Low Doses

STROKEAHA: July 10, 2014 Background and Purpose—It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. Methods—We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treated within 4.5 hours after symptom onset were included. […]

Summary of evidence-based guideline update: Prevention of stroke in nonvalvular atrial fibrillation

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Neurology February 25, 2014 Objective: To update the 1998 American Academy of Neurology practice parameter on stroke prevention in nonvalvular atrial fibrillation (NVAF). How often do various technologies identify previously undetected NVAF? Which therapies reduce ischemic stroke risk with the least risk of hemorrhage, including intracranial hemorrhage? The complete guideline on which this summary is based is […]

Stroke Incidence and Mortality Trends in US Communities, 1987 to 2011

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JAMA: July 16, 2014 Importance  Prior studies have shown decreases in stroke mortality over time, but data on validated stroke incidence and long-term trends by race are limited. Objective  To study trends in stroke incidence and subsequent mortality among black and white adults in the Atherosclerosis Risk in Communities (ARIC) cohort from 1987 to 2011. Design, Setting, and Participants  Prospective cohort […]

Trends in 10-Year Survival of Patients With Stroke Hospitalized Between 1980 and 2000

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STROKEAHA: uly 15, 2014 Abstract Background and Purpose—We report on trends in poststroke survival, both in the early period after stroke and over the long term. We examine these trends by stroke subtype. Methods—The Minnesota Stroke Survey is a study of all hospitalized patients with acute stroke aged 30 to 74 years in the Minneapolis–St Paul […]

Status of Cardiovascular Disease and Stroke in Hispanics/Latinos in the United States

CIR: July 2014 Background and Purpose—This American Heart Association (AHA) scientific statement provides a comprehensive overview of current evidence on the burden cardiovascular disease (CVD) among Hispanics in the United States. Hispanics are the largest minority ethnic group in the United States, and their health is vital to the public health of the nation and […]

Chronic Stress, Depressive Symptoms, Anger, Hostility, and Risk of Stroke and Transient Ischemic Attack in the Multi-Ethnic Study of Atherosclerosis

STROKEAHA: July 10, 2014 Background and Purpose—This study investigated chronic stress, depressive symptoms, anger, and hostility in relation to incident stroke and transient ischemic attacks in middle-aged and older adults. Methods—Data were from the Multi-Ethnic Study of Atherosclerosis (MESA), a population-based cohort study of 6749 adults, aged 45 to 84 years and free of clinical […]

Racial differences in disability after stroke

Neurology: June 27, 2014 Objective: We sought to characterize racial differences in disability among older stroke survivors. Methods: A cross-sectional study of 806 self-reported stroke survivors from the 2011 National Health and Aging Trends Study was performed. Race was based on self-report. Primary outcome was activity limitations (requiring assistance with mobility, self-care, and household activities). Secondary outcome was […]

New Drugs and Technologies: Left Atrial Appendage Closure to Prevent Stroke in Patients With Atrial Fibrillation

CIRCULATIONAHA: 7/8/14 trial fibrillation (AF) is the most common sustained arrhythmia and is associated with substantial morbidity. The prevalence of AF in the United States is expected to rise to between 5.6 and 12 million in 2050.1 AF is associated with a 4- to 5-fold increased risk of ischemic stroke after adjustment for other risk factors,2 and paroxysmal, […]

New oral anticoagulants in patients with atrial fibrillation

The Lancet: July 5, 2014 From a meta-analysis of four studies, Christian Ruff and colleagues1 concluded that use of new oral anticoagulants (NOACs) in patients with atrial fibrillation results in a decreased incidence of stroke and mortality when compared with warfarin. However, the mean time in therapeutic range (TTR) was less than 65% in the warfarin group […]

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