Clinical Trials
Friday, August 28th, 2015
Stroke, 11 June 2015 Background and Purpose—Less than 25% of stroke patients arrive to an emergency department within the 3-hour treatment window. Stroke Warning Information and Faster Treatment (SWIFT) compared an interactive intervention (II) with enhanced educational (EE) materials on recurrent stroke arrival times in a prospective cohort of multiethnic stroke/transient ischemic attack survivors.… Conclusions—There […]
Clinical Trials
Friday, August 28th, 2015
N Engl J Med, 12 March 2015 Background Among patients with a proximal vessel occlusion in the anterior circulation, 60 to 80% of patients die within 90 days after stroke onset or do not regain functional independence despite alteplase treatment. We evaluated rapid endovascular treatment in addition to standard care in patients with acute ischemic […]
Therapies
Friday, August 28th, 2015
J Am Heart Assoc, 12 August 2015 Background Differences in activation of emergency medical services (EMS) may contribute to racial/ethnic and sex disparities in stroke outcomes. The purpose of this study was to determine whether EMS use varied by race/ethnicity and sex among a current, diverse national sample of hospitalized acute stroke patients.… Conclusions EMS […]
Therapies
Friday, August 28th, 2015
Stroke, 2 June 2015 Background and Purpose—Little is known about how regions vary in their use of thrombolysis (intravenous tissue-type plasminogen activator and intra-arterial treatment) for acute stroke. We sought to determine regional variation in thrombolysis treatment and investigate the extent to which regional variation is accounted for by patient demographics, regional factors, and elements […]
Therapies
Friday, August 28th, 2015
Stroke, 13 February 2013 Background and Purpose—We sought to determine hospital and patient characteristics associated with the use of endovascular therapy for acute ischemic stroke and to analyze trends in clinical outcome.… Conclusion—The use of endovascular therapy increased modestly nationally from 2003 to 2012 and decreased in 2013. Clinical outcomes improved notably from 2010 to […]
Therapies
Friday, August 28th, 2015
J Am Heart Assoc, 9 January 2015 Background One third of patients presenting with initially mild strokes have unfavorable outcomes, and the efficacy of intravenous thrombolysis (IVT) in this population has not been proven. This study aimed to evaluate the comparative effectiveness of standard care with IVT versus without IVT in mild stroke patients.… Conclusions […]
Therapies
Friday, August 28th, 2015
Stroke, 6 January 2015 Stroke is a medical emergency and care provided in the first hours is critical in shaping patients’ long-term recovery and prognosis. There is robust evidence demonstrating significant reductions in death and disability with early interventions in acute stroke care, including antiplatelet therapy stroke unit (SU) care and thrombolysis. International clinical guidelines […]
Atrial Fibrillation, Guidelines
Friday, August 28th, 2015
J Am Heart Assoc, 6 April 2015 Background Although guidelines for antiarrhythmic drug therapy in atrial fibrillation (AF) were published in 2006, it remains uncertain whether adherence to these guidelines affects patient outcomes.… Conclusions Adherence to published guidelines in the antiarrhythmic management of AF is associated with improved patient outcomes. Read more.
Guidelines
Friday, August 28th, 2015
JAMA Intern Med, November 2014 The American College of Cardiology/American Heart Association (ACC/AHA) guidelines are frequently used to guide cardiovascular care. Randomized controlled trials (RCTs) are considered to be the highest level of evidence and are cited in these guidelines whenever available. However, RCTs can have limited external validity. To examine their generalizability, we examined […]
Guidelines
Friday, August 28th, 2015
Stroke, 28 October 2014 The aim of this updated statement is to provide comprehensive and timely evidence-based recommendations on the prevention of stroke among individuals who have not previously experienced a stroke or transient ischemic attack. Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, […]
