Basic Science Advances for Clinicians

Therapies Saturday, June 2nd, 2012

Stroke.ahajournals.org: April 24, 2012

Progress in Sonothrombolysis for the Treatment of Stroke

In 1974, Sobbe et al1 applied 26.5-kHz ultrasound (US) to recanalize thrombosed iliofemoral arteries in dogs with minimal complications. These pioneer efforts were followed by studies showing that catheter-based or transcutaneous US can enhance the effect of fibrinolytic agents in recanalizing thrombosed arteries,2–8 thus paving the way for first clinical studies evaluating the adjunct effect of US in treating patients with ischemic stroke. Read more

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