Atrial Remodeling Role in Atrial Fibrillation Ablation

Atrial Fibrillation Sunday, January 13th, 2013

Jafib: January 13th, 2013

There have been considerable advances in understanding the relationship of atrial fibrillation (AF) and atrial remodelling suggesting that remodelling states have a significant impact on treatment results.

Therefore, we reviewed the literature about the role of atrial remodelling in AF treatment, focussing on AF ablation.

Atrial fibrillatory activity, dominant frequencies (DF), complex fractionated atrial electrograms (CFAE) as well as function, volume, and fibrosis of the – especially left – atrium are most important characteristics for electrical, contractile, and structural remodelling predicting success of AF treatment. In particular, the results of AF ablation, either using catheter-based or surgical techniques, predominantly depend on the degree of structural remodelling, namely dilatation and fibrosis of the left atrium. Read More

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