Cognitive Impairment Associated With Atrial Fibrillation

Ann Intern Medicine: March 5, 2013

Background: Atrial fibrillation (AF) has been linked with an increased risk for cognitive impairment and dementia.

Purpose: To complete a meta-analysis of studies examining the association between AF and cognitive impairment.

Data Sources: Search of MEDLINE, PsycINFO, Cochrane Library, CINAHL, and EMBASE databases and hand search of article references.

Study Selection: Prospective and nonprospective studies reporting adjusted risk estimates for the association between AF and cognitive impairment.

Data Extraction: Two abstracters independently extracted data on study characteristics, risk estimates, methods of AF and outcome ascertainment, and methodological quality. Read more

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