Intracluster correlation coefficients and reliability of randomized multicenter stroke trials within VISTA

Wiley: 9/5/13

Reliable estimates of intracluster correlation coefficients (ICCs) for specific outcome measures are crucial for sample size calculations of future cluster randomized trials. ICCs indicate the proportion of data variability that is explained by defined levels of clustering.

In this manuscript, we present potentially valuable and reliable estimates of ICCs for specific baseline and follow-up data.

ICCs were estimated from linear and generalized linear mixed models using maximum likelihood estimation for common measures used in stroke research, including modified Rankin Scale (mRS), National Institutes of Health Stroke Scale (NIHSS), and Barthel Index (BI). Read more