A Randomised Controlled Trial of Catheter Ablation versus Medical Treatment of Atrial Fibrillation in Heart Failure (THE CAMTAF TRIAL)
Clinical Trials Thursday, January 9th, 2014CIRCEP: January 1, 2014
Background—Restoring sinus rhythm in patients with heart failure (HF) and atrial fibrillation (AF) may improve left ventricular (LV) function and HF symptoms. We sought to compare the impact of a catheter ablation strategy with that of a medical rate control strategy in patients with persistent AF and HF.
Methods and Results—Patients with persistent AF, symptomatic HF, and LV ejection fraction (EF) < 50% were randomised to catheter ablation or medical rate control. The primary end-point was the difference between groups in LV EF at 6 months. Baseline LVEF was 32 ± 8% in the ablation group and 34 ± 12% in the medical group. 26 patients underwent catheter ablation and 24 patients were rate controlled. Read More