Adenosine-Induced Pulmonary Vein Ectopy as a Predictor of Recurrent Atrial Fibrillation Following Pulmonary Vein Isolation

Atrial Fibrillation Friday, November 22nd, 2013

AHA: 11/15/13

Background—Adenosine (ADO) can unmask dormant pulmonary vein (PV) conduction following PV isolation. ADO can also induce ectopy in electrically silent PVs following isolation, possibly via activation of autonomic triggers. We sought to identify the implications of ADO-induced PV ectopy for atrial fibrillation (AF) recurrence following PV isolation.

Methods and Results—A total of 152 patients (age 60 ± 11 years; 63% paroxysmal AF) undergoing PV isolation for AF were studied. After each PV was isolated, ADO was administered and the presence of ADO-induced PV reconnection and PV ectopy were recorded. Dormant conduction was targeted with additional ablation. ADO-induced PV ectopy was seen in 45 (30%) patients and dormant conduction was seen in 44 (29%) patients. Read More

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