Antihypertensive treatment can prevent stroke and cognitive decline

News Thursday, March 14th, 2013

Nature: March 1, 2013

Hypertension is a highly prevalent risk factor for stroke and dementia, and is the greatest risk factor for small-vessel disease—a frequent cause of lacunar infarction and intracerebral haemorrhage. Lacunar and cortical strokes contribute to the development of dementia in patients with, and in those without, Alzheimer disease pathology; this relationship between stroke and dementia is probably mediated by ischaemia-induced neuroinflammation. Antihypertensive treatment can reduce the risk of stroke and dementia, but requires optimal blood pressure targets to be established for individual patients. Read more

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