Antithrombotic treatment of atrial fibrillation: New insights

Atrial Fibrillation Friday, October 5th, 2012

Sciencedirect.com: October 6, 2012
The incidence and prevalence of atrial fibrillation are quickly increasing, mainly due to the ageing of the population. Atrial fibrillation is, to date, a problem of public health. Atrial fibrillation is associated to a five-fold risk of stroke, which may be identified by score risks, such as CHADS2 score. The classical antithrombotic treatment of atrial fibrillation is based on vitamin K antagonists. Trials made in the 90’s have clearly shown that vitamin K antagonists were able to decrease stroke risk by about 60%. New oral anticoagulants are now available on the market to treat patients with atrial fibrillation. These drugs are Dabigatran which has demonstrated an interest in the RE-LY trial. Two doses may be prescribed, 110 mg bid and 150 mg bid.  read more

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