Basic Science for the Clinical Electrophysiologist

Atrial Fibrillation Monday, October 22nd, 2012

American Heart Association, Inc:  October 1, 2012
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice, affecting 1.5% to 2.0% of the population in the developed world. The lifetime risk for the development of AF is ≈1 in 4 men and women aged ≥40 years.1,2 A 2.5- to 3.0-fold increase in the incidence of AF has been projected during the next 50 years,3 and with the aging population, both the prevalence and economic impact of AF are increasing progressively.4 In addition, current therapeutic options are suboptimal, some even proarrhythmic. For these reasons, it is of clinical importance to identify and elucidate the underlying mechanisms of this arrhythmia for the identification of new therapeutic targets. Read more

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