Better care must be taken to prevent or account for missing data in clinical trials

Ns.umich.edu: 10/3/12

ANN ARBOR, Mich.—Large amounts of missing data in clinical trials can undermine the scientific credibility of the studies, according to a special report by an expert panel commissioned by the National Research Council.

The panel, chaired by Roderick Little, the Richard D. Remington Collegiate Professor of Biostatistics at the University of Michigan School of Public Health, also found that common current methods for analysis do not adequately adjust for missing data, sometimes leading to unjustified conclusions about the efficacy of drugs, biologic products and some medical devices. Read more

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