Bridging Therapy in Acute Ischemic Stroke

A Systematic Review and Meta-Analysis

Ahajournals: Mikael Mazighi, MD, PhD; Elena Meseguer, MD; Julien Labreuche, BS; Pierre Amarenco, MD. May 1, 2012.

Background and Purpose—Pending the results of randomized controlled trials, the benefit and safety of bridging therapy (combined intravenous and intra-arterial thrombolysis) remain to be determined. The aim of this analysis was to give reliable estimates of efficacy and safety outcomes of bridging therapy.

Methods—We conducted a systematic review of all studies using bridging therapy published between January 1966 and March 2011. Read more

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