Atrial Fibrillation
Tuesday, June 18th, 2013
Science Direct: February 1, 2013 Abstract Prior research found that Americans born in 6 southeastern states (the AF-risk zone) had elevated risk of AF-related mortality, but no mechanisms were identified. We hypothesized the association between AF-related mortality and AF-risk zone birth is explained by indicators of childhood social disadvantage or adult risk factors. In 24,323 participants […]
Atrial Fibrillation, Guidelines
Tuesday, June 18th, 2013
AHRQ: June 4, 2013 Objectives. There are two generally accepted strategies for managing atrial fibrillation (AF): rate control and rhythm control. However, within each strategic approach there are a large number of potential pharmacological and nonpharmacological therapies, and the comparative safety and effectiveness of these therapies—both within and between strategies—are uncertain. Data sources. We searched […]
Atrial Fibrillation
Tuesday, June 18th, 2013
Annals of Neurology: June 17, 2013 Objective Long-term data on recurrent vascular events after young stroke are limited. Our objective was to examine the long-term risk of recurrent vascular events after young stroke. Methods We prospectively included 724 consecutive patients with a first-ever transient ischemic attack (TIA), ischemic stroke, or intracerebral hemorrhage (ICH), aged 18 […]
Atrial Fibrillation
Sunday, June 16th, 2013
The Lancet – June 5, 2013 Background VKORC1 and CYP2C9 are important contributors to warfarin dose variability, but explain less variability for individuals of African descent than for those of European or Asian descent. We aimed to identify additional variants contributing to warfarin dose requirements in African Americans. Methods We did a genome-wide association study of discovery and […]
Atrial Fibrillation
Sunday, June 16th, 2013
Neurology- June 5, 2013 Objective: We sought to determine whether in the absence of clinical stroke, people with atrial fibrillation experience faster cognitive decline than people without atrial fibrillation. Methods: We conducted a longitudinal analysis in the Cardiovascular Health Study, a community-based study of 5,888 men and women aged 65 years and older, enrolled in 1989/1990 or 1992/1993. […]
Atrial Fibrillation
Sunday, June 16th, 2013
Cochrane Summaries – 6/4/13 Atrial fibrillation is a chronic condition that is characterised by an irregular heart beat. This irregularity of the heart rhythm places people with atrial fibrillation at greater risk of forming blood clots and subsequently increases their risk of stroke. The most common treatment for reducing the risk of stroke is medication with oral drugs that ‘thin’ the blood, […]
Atrial Fibrillation
Sunday, June 16th, 2013
Heart Bmj -5/29/13 Objective To examine the prevalence of atrial fibrillation (AF) and stroke risk by ethnic group in south and east London; to compare classification with CHA2DS2VASc and CHADS2; to examine the appropriateness of anticoagulant treatment and historic trends in prescribing by gender, age, and ethnicity. Design Cross-sectional study. Setting Routine general practice records from south and […]
Atrial Fibrillation
Sunday, June 16th, 2013
PLOS one – 5/29/13 Background Gender-based clinical differences are increasingly being identified as having significant influence on the outcomes of patients with cardiovascular disease (CVD), including atrial fibrillation (AF). Objective To perform detailed clinical phenotyping on a cohort of hospitalised patients with chronic forms of AF to understand if gender-based differences exist in the clinical […]
Atrial Fibrillation
Friday, June 7th, 2013
JACC: June 4, 2013 Most clinicians would like to be able to accurately estimate the risk of adverse outcomes, especially if this information could guide management or treatment decisions to lower the risk for an individual. In the case of atrial fibrillation (AF), the most common cardiac arrhythmia, more accurate prediction of its most feared […]
Atrial Fibrillation
Friday, June 7th, 2013
PLOS One: May 24, 2013 Background A prolonged PR interval is a sign of increased risk of cardiac arrhythmia. Recent genome-wide association studies found that the single-nucleotide polymorphism (SNP) rs3825214 in T-box 5 (TBX5) was positively associated with PR interval, QRS duration, QT interval, and common arrhythmia disorders such as atrial fibrillation (AF) and advanced […]
