Atrial Fibrillation
Monday, March 11th, 2013
Ann Intern Medicine: March 5, 2013 Background: Atrial fibrillation (AF) has been linked with an increased risk for cognitive impairment and dementia. Purpose: To complete a meta-analysis of studies examining the association between AF and cognitive impairment. Data Sources: Search of MEDLINE, PsycINFO, Cochrane Library, CINAHL, and EMBASE databases and hand search of article references. Study Selection: Prospective and […]
Atrial Fibrillation
Monday, March 11th, 2013
CIRCULATIONAHA: March 5, 2013 Background—Electrocardiographic QRS duration, a measure of cardiac intraventricular conduction, varies ~2-fold in individuals without cardiac disease. Slow conduction may promote reentrant arrhythmias. Methods and Results—We performed a genome-wide association study (GWAS) to identify genomic markers of QRS duration in 5,272 individuals without cardiac disease selected from electronic medical record (EMR) algorithms at […]
Atrial Fibrillation
Monday, March 11th, 2013
CIRCRESAHA: March 1, 2013 Of all the cardiac arrhythmias seen in clinical practice, atrial fibrillation (AF) and ventricular tachycardia/fibrillation (VT/VF) are among the leading causes of morbidity and mortality in the developed world. AF is the most common sustained arrhythmia and is associated with an increased risk of stroke, heart failure, dementia, and death. In developed […]
Atrial Fibrillation
Wednesday, March 6th, 2013
European Heart Journal: February 26, 2013 Aims Atrial fibrillation (AF) is associated with adverse outcome. Whether recently discovered genetic risk markers improve AF risk prediction is unknown. Methods and results We derived and validated a novel AF risk prediction model from 32 possible predictors in the Women’s Health Study (WHS), a cohort of 20 822 women without cardiovascular […]
Atrial Fibrillation
Wednesday, March 6th, 2013
STROKEAHA: February 26, 2013 Background and Purpose—Atrial fibrillation (AF) has been associated with cognitive decline independent of stroke, suggesting additional effects of AF on the brain. We aimed to assess the association between AF and brain function and structure in a general elderly population. Methods—This is a cross-sectional analysis of 4251 nondemented participants (mean age, 76±5 […]
Atrial Fibrillation
Wednesday, March 6th, 2013
CIRCEP: February 26, 2013 Background—Uninterrupted anticoagulation with warfarin during radiofrequency catheter ablation (RFA) of atrial fibrillation (AF) is associated with a lower risk of periprocedural complications than when warfarin is temporarily discontinued. However, the optimal international normalized ratio (INR) levels during RFA have not been defined. Methods and Results—In this retrospective analysis, RFA was performed in […]
Atrial Fibrillation
Wednesday, March 6th, 2013
JAMA Intern Medicine: February 25, 2013 Oral vitamin K antagonists, such as warfarin, are among the most commonly prescribed and potentially dangerous classes of medications.1 For many high-risk drugs, such as warfarin, there is a strong link between patient knowledge about the medication and their safe use.2 For warfarin, provision of high-quality education improves compliance, increases time in the therapeutic […]
Atrial Fibrillation
Wednesday, March 6th, 2013
Sleep Medicine: January 21, 2013 Background Obstructive sleep apnea (OSA) has been shown to be an independent risk factor for ischemic stroke and may increase the risk of atrial fibrillation (AF) by up to fourfold. Given these relationships, it is possible that OSA may provide a link between stroke and AF. A case-control study was conducted […]
Atrial Fibrillation
Tuesday, February 26th, 2013
U.S. Pharmacist: February 20, 2013 ABSTRACT: Antiarrhythmic therapy for atrial fibrillation comprises a broad range of medications that are used to prevent conversion from normal sinus rhythm to atrial fibrillation, as well as to control symptoms. These medications, although effective, require extensive monitoring and patient education. The antiarrhythmics most commonly used to maintain normal sinus […]
Atrial Fibrillation
Tuesday, February 26th, 2013
Europace Oxford Journals: February 20, 2013 Aims Cryoballoon ablation (CBA; Arctic Front, Medtronic) has proven very effective in achieving pulmonary vein isolation. Real-time three-dimensional transoesophageal echocardiography (RT 3D TEE) is a novel technology, which permits detailed visualization of cardiac structures in a 3D perspective. The aim of the present study was to assess the feasibility, advantages, and […]
