Contemporary Reviews in Cardiovascular Medicine, Shared Decision Making in Atrial Fibrillation, Where We Are and Where We Should Be Going

CIRCULATIONAHA: 2/11/14 You are seeing Mr Roberts, a 69-year-old retired office manager referred from the emergency department for treatment of atrial fibrillation (AF). He presented the previous night to the emergency department with shortness of breath and palpitations and was found to be in AF with a rapid ventricular response and a heart rate of 140 […]

A National Assessment of Warfarin Anticoagulation Therapy for Stroke Prevention in Atrial Fibrillation

CIRCULATIONAHA:  February 3, 2014 Background—Anticoagulation control with warfarin, as assessed by the international normalized ratio (INR), is challenging. Time in the therapeutic range (TTR) has been inversely correlated with major hemorrhage, thrombosis, and mortality. Quest Diagnostics offers standardized INR laboratory testing services to approximately half of U.S. physician practices. To inform national stroke prevention strategies, […]

Effect of Radiofrequency Catheter Ablation for Atrial Fibrillation on Morbidity and Mortality

Circulation: Arrhythmia and Electrophysiology: January 20, 2014 Background—This study examined the effect of radiofrequency catheter ablation (RFA) on reducing morbidity and mortality among patients with atrial fibrillation (AF). Methods and Results—A retrospective cohort of patients with AF without prior stroke or heart failure (HF) who underwent RFA between 2003 and 2009 was identified using Taiwan’s National […]

Variations in Etiology and Management of Atrial Fibrillation in a Prospective Registry of 15,400 Emergency Department Patients in 46 Countries: The RE-LY AF Registry

CIRCULATIONAHA: January 24, 2014 Background—Atrial fibrillation (AF) is the most common sustained arrhythmia; however little is known about patients in a primary care setting from high, middle and low-income countries. Methods and Results—This prospective registry enrolled patients presenting to an emergency department with AF at 164 sites in 46 countries representing all inhabited continents. Patient characteristics […]

A-Fib Doesn’t Mean You’re Banished to the Sidelines

HealthDay Reporter: FRIDAY, Jan. 10 (HealthDay News) — Cutting back on exercise, or stopping altogether, might seem like the right move for people whose heart beats too fast and erratically, a condition called atrial fibrillation. But that’s not necessarily so. In fact, staying active — biking, swimming, perhaps even playing pickup basketball, for instance — might […]

Detection of Atrial Fibrillation After Ischemic Stroke or Transient Ischemic Attack

STROKEAHA: January 2, 2014 Background and Purpose—Atrial fibrillation (AF) confers a high risk of recurrent stroke, although detection methods and definitions of paroxysmal AF during screening vary. We therefore undertook a systematic review and meta-analysis to determine the frequency of newly detected AF using noninvasive or invasive cardiac monitoring after ischemic stroke or transient ischemic attack. […]

Atrial Fibrillation and the Risk of Myocardial Infarction

JAMA: January 2014 Importance  Myocardial infarction (MI) is an established risk factor for atrial fibrillation (AF). However, the extent to which AF is a risk factor for MI has not been investigated. Objective  To examine the risk of incident MI associated with AF. Design, Setting, and Participants  A prospective cohort of 23 928 participants residing in the continental United […]

Awareness of the Role of Atrial Fibrillation as a Cause of Ischemic Stroke

STROKEAHA: December 19, 2013 Atrial fibrillation (AF) in the presence of mitral stenosis, a consequence of rheumatic heart disease, was long recognized as the basis for cerebral infarction. Although it had long been acknowledged that atrial stasis resulting from mitral stenosis, often in the presence of AF, predisposed to thrombus formation, investigators questioned whether the AF […]

Initiation of warfarin in patients with atrial fibrillation: early effects on ischaemic strokes

Eur Heart J: December 18, 2013 Aims An increased risk of stroke was observed in two atrial fibrillation (AF) trials of oral factor Xa inhibitors, when patients were transitioned to open label warfarin at the end of the study. The objective of this study is to determine whether initiation of warfarin is associated with an increased risk […]

Antihypertensive treatment and risk of atrial fibrillation: a nationwide study

Eur Heart J: December 17, 2013 Aims To examine the associations between antihypertensive treatment with angiotensin-converting enzyme inhibitors (ACEis) or angiotensin receptor blockers (ARBs), β-blockers, diuretics, or calcium-antagonists, and risk of atrial fibrillation. We examined these associations using the entire Danish population from 1995 through 2010. Methods and results Excluding medication used in atrial fibrillation, we matched individuals […]

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