Clinical Trials
Friday, August 31st, 2012
Thelancet.com: 8/25/12 Thrombolysis with intravenous alteplase is the only approved treatment for acute ischaemic stroke. After alteplase-induced recanalisation, reocclusion occurs in 14—34% of patients, probably because of platelet activation. Early administration of antiplatelet therapy after alteplase could reduce the risk of reocclusion and improve outcome. We compared the effects of early addition of intravenous aspirin to […]
Clinical Trials
Wednesday, August 29th, 2012
Stroke.ahajournals.org: August 21, 2012 Our goal was to investigate whether initial ischemic lesion pattern can predict stroke recurrence in patients with symptomatic intracranial arterial stenosis. Methods—Of the Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis (TOSS)-2 trial participants, we included patients who underwent diffusion-weighted imaging and fluid attenuation inversion recovery imaging at baseline with a follow-up […]
Clinical Trials
Thursday, August 23rd, 2012
American College of Cardiology Foundation: August 2012 Increasingly, the practice of medicine has relied on applicable and available evidence to deliver quality care. Cardiovascular medicine has led the way using numerous clinical trials as the basis of clinical practice guidelines. However, despite the strong association of aging with the development of cardiovascular disease, randomized clinical trials rarely […]
Clinical Trials
Thursday, August 23rd, 2012
Nih.gov: 8/22/12 An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health. Inflammation, […]
Clinical Trials
Thursday, August 23rd, 2012
Advances in technologies and knowledge are creating new avenues for research and opportunities for the discovery and clinical development of innovative therapies and diagnostics. However, despite these opportunities, only a small fraction of investigational products are successfully developed into cures and therapies that can be accessed by patients. One response to the ever-widening gap between […]
Clinical Trials
Thursday, August 23rd, 2012
Medicalxpress.com: August 17, 2012 in Medical research With two new NIH awards, a researcher at UC’s College of Allied Health Sciences hopes to learn how augmentative and alternative communication (AAC) devices can help these patients continue to communicate. Assistant Professor of Communication Sciences and Disorders Aimee Dietz, PhD, says that for many post-stroke patients, aphasia does not completely […]
Clinical Trials
Monday, August 20th, 2012
Content.onlinejacc.org: 8/21/12 This study sought to perform an indirect comparison analysis of dabigatran etexilate (2 doses), rivaroxaban, and apixaban for their relative efficacy and safety against each other. Background Data for warfarin compared against the new oral anticoagulants (OACs) in large phase III clinical trials of stroke prevention in atrial fibrillation (AF) are now available for the […]
Clinical Trials
Monday, August 20th, 2012
Sstroke.ahajournals.org: 8/14/12. The increasing availability of robot-assisted therapy (RT), which provides quantifiable, reproducible, interactive, and intensive practice, holds promise for stroke rehabilitation, but data on its dose–response relation are scanty. This study used 2 different intensities of RT to examine the treatment effects of RT and the effect on outcomes of the severity of initial motor […]
Clinical Trials
Monday, August 20th, 2012
Circheartfailure.ahajournals.org: August 14, 2012 Cardiac resynchronization (CRT) prolongs survival in patients with systolic heart failure and QRS prolongation. However; most trials excluded patients with permanent atrial fibrillation (AF). Methods and Results—The RAFT trial randomized patients to an implantable defibrillator (ICD) or ICD + CRT; stratified by the presence of permanent AF. Patients with permanent AF were […]
Clinical Trials
Monday, August 20th, 2012
Circep.ahajournals.org: 7/7/12 We describe a novel fluoroscopy coregistered, 4-dimensional catheter tracking technology (MediGuide Technology [MGT]) used for treatment of patients with atrial fibrillation. The aim of the study was to investigate (1) the feasibility of nonfluoroscopic catheter manipulation within dynamic left atrial chamber models; (2) the integration of the technology into an established electroanatomical mapping system; […]
