Pharmaceutical Innovation and Longevity Growth in 30 Developing and High-income Countries, 2000-2009

Nber.org: 7/19/12 We examine the impact of pharmaceutical innovation, as measured by the vintage of prescription drugs used, on longevity, using longitudinal, country-level data on 30 developing and high-income countries during the period 2000-2009. We control for fixed country and year effects, real per capita income, the unemployment rate, mean years of schooling, the urbanization rate, […]

Returning to Paid Employment after Stroke: The Psychosocial Outcomes In StrokE (POISE) Cohort Study

Plosone.org: 7/25/12. To determine which early modifiable factors are associated with younger stroke survivors’ ability to return to paid work in a cohort study with 12-months of follow-up conducted in 20 stroke units in the Stroke Services NSW clinical network. Read More

Medication coaching program for patients with minor stroke or TIA: A pilot study

Biomedcentral.com: 7/25/12. Patients who are hospitalized with a first or recurrent stroke often are discharged with new medications or adjustment to the doses of pre-admission medications, which can be confusing and pose safety issues if misunderstood. The purpose of this pilot study was to assess the feasibility of medication coaching via telephone after discharge in patients […]

A Comprehensive Evaluation of Rhythm Monitoring Strategies for the Detection of Atrial Fibrillation Recurrence: Insights from 647 Continuously Monitored Patients and Implications for Monitoring After Therapeutic Interventions

Circ.ahajournals.org: 7/23/12. Intermittent rhythm monitoring (IRM) to detect atrial fibrillation (AF) recurrence is employed to evaluate the success of therapeutic interventions. In a large population of continuously monitored (CM) patients, we investigated the sensitivity of various frequency and duration IRM strategies on the detection of AF recurrence, the dynamics behind AF recurrence detection and describe […]

Earlier Blood Pressure-Lowering and Greater Attenuation of Hematoma Growth in Acute Intracerebral Hemorrhag

Stroke.ahajournals.org: 6/7/12. The INTEnsive blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT) pilot study showed that early intensive blood pressure-lowering can attenuate hematoma growth in acute intracerebral hemorrhage. The present analysis aimed to determine the treatment effects on hematoma growth by time from intracerebral hemorrhage onset to randomization. Read More

Theta Burst Stimulation Over the Right Broca’s Homologue Induces Improvement of Naming in Aphasic Patients

Stroke.ahajournals.org: 5/10/12. Improvements of language production in aphasic patients have been reported following repeated 1-Hz transcranial magnetic stimulation over the nondamaged right hemisphere. Most studies examined aphasic patients in the chronic phase. The effect of transcranial magnetic stimulation application in acute or subacute patients has not been systematically studied. We aimed to evaluate whether continuous […]

Treatment of Atrial Fibrillation by the Ablation of Localized Sources

American College of Cardiology Foundation: 7/19. We hypothesized that human atrial fibrillation (AF) may be sustained by localized sources (electrical rotors and focal impulses), whose elimination (focal impulse and rotor modulation [FIRM]) may improve outcome from AF ablation. Background  Catheter ablation for AF is a promising therapy, whose success is limited in part by uncertainty in the […]

Reduction of Long‐Term Care Dependence After an 8‐Year Primary Care Prevention Program for Stroke and Dementia: The INVADE Trial

American Heart Association, Inc: July 17, 2012. Stroke and dementia are the major causes for long‐term care (LTC) dependence in old age. This intervention trial compared a multidomain prevention program for stroke and dementia with usual medical care in reducing the need for LTC. Methods and Results The Intervention Project on Cerebrovascular Disease and Dementia in […]

Cortical Changes After Mental Imagery Training Combined With Electromyography-Triggered Electrical Stimulation in Patients With Chronic Stroke

Stroke.ahajournals.org: July 12, 2012. Paresis of the upper extremity after stroke is not effectively solved by existing therapies. We investigated whether mental imagery training combined with electromyogram-triggered electric stimulation improved motor function of the paretic upper extremity in patients with chronic stroke and induced cortical changes. Methods—Fourteen subjects with chronic stroke (≥12 months) were randomly allocated […]

A cluster randomized trial to assess the effect of clinical pathways for patients with stroke: results of the Clinical Pathways for Effective and Appropriate Care Study

BMC Medicine: July 10, 2012. Clinical pathways (CPs) are used to improve the outcomes of acute stroke, but their use in stroke care is questionable, because the evidence on their effectiveness is still inconclusive. The objective of this study was to evaluate whether CPs improve the outcomes and the quality of care provided to patients after […]

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