Clinical Trials
Saturday, July 21st, 2012
Sciencedirect.com: July 6 2012 Dronedarone is a therapy for the treatment of patients with paroxysmal and persistent atrial fibrillation or atrial flutter. According to results in the ATHENA trial, dronedarone on top of standard of care (SOC) decreases the risk of cardiovascular hospitalizations or death by 24% compared with SOC alone. Objectives A patient-level health economic […]
Clinical Trials
Thursday, July 12th, 2012
Medicalxpress.com: 7/11/12. The new treatment is promising news for people with speech and language disorders that result from diseases within the nervous system. Professor Bruce Murdoch of the Centre for Neurogenic Communication Disorders Research within UQ’s School of Health and Rehabilitation Sciences said preliminary trials of the new treatment were positive in the effective treatment of these speech […]
Clinical Trials
Thursday, July 12th, 2012
Stroke.ahajournals.org: July 7, 2012. We describe a novel fluoroscopy co-registered 4D catheter tracking technology (MGT) used for treatment of patients with atrial fibrillation (AF). The aim of the study was to investigate (i) feasibility of non-fluoroscopic catheter manipulation within dynamic left atrial chamber models, (ii) integration of the technology into an established electroanatomical mapping system […]
Clinical Trials
Thursday, July 12th, 2012
Stroke.ahajournals.org: July 3, 2012. Bone marrow mononuclear cell (BM-MNC) intra-arterial transplantation improves recovery in experimental models of ischemic stroke. We aimed to assess the safety, feasibility, and biological effects of autologous BM-MNC transplantation in patients with stroke. Methods—A single-blind (outcomes assessor) controlled Phase I/II trial was conducted in patients with middle cerebral artery stroke. Autologous […]
Clinical Trials
Wednesday, July 11th, 2012
Iospress.metapress.com: 7/5/12. Purpose: Transcranial direct current stimulation (tDCS) combined with swallowing training might improve swallowing function in patients with post-stroke dysphagia. We investigate the effects of transcranial direct current stimulation (tDCS) combined with swallowing training on post-stroke dysphagia. Methods: Sixteen patients with post-stroke dysphagia, diagnosed using video fluoroscopic swallowing (VFSS), were randomly assigned into two groups: […]
Clinical Trials
Wednesday, July 11th, 2012
Brain.oxfordjournals.org: July 2, 2012. Hemispatial neglect following right-hemisphere stroke is a common and disabling disorder, for which there is currently no effective pharmacological treatment. Dopamine agonists have been shown to play a role in selective attention and working memory, two core cognitive components of neglect. Here, we investigated whether the dopamine agonist rotigotine would have a […]
Clinical Trials
Wednesday, July 11th, 2012
News-medical.net: Published on July 2, 2012 at 11:45 PM: A new approach to testing medical treatment options could ensure that more patients get the most beneficial treatment for them – but still yield valuable research results that stand up to scientific scrutiny. The approach tries to overcome a huge chicken-and-egg problem in medical research: Not enough […]
Clinical Trials
Wednesday, July 11th, 2012
Ctj.sagepub.com: July 2, 2012. There is a growing appreciation that our current approach to clinical research leaves important gaps in evidence from the perspective of patients, clinicians, and payers wishing to make evidence-based clinical and health policy decisions. This has been a major driver in the rapid increase in interest in comparative effectiveness research (CER), which […]
Clinical Trials
Wednesday, July 11th, 2012
Onlinelibrary.wiley.com: 6/19/12. The mortality and morbidity associated with stroke makes the development of new drugs a research priority. Recent unsuccessful clinical trials have reduced enthusiasm for the development of neuroprotective drugs. Here, we use empirical evidence derived from systematic reviews of stroke drug development to identify stages of drug development which might be improved. We then […]
Clinical Trials
Thursday, June 28th, 2012
Stroke.ahajournals.org: July 1, 2012. Background and Purpose—The purpose of this study was to test the feasibility of conducting a randomized controlled trial to study the effectiveness of self-managed computer treatment for people with long-standing aphasia after stroke. Method—In this pilot single-blinded, parallel-group, randomized controlled trial participants with aphasia were allocated to self-managed computer treatment with volunteer […]
