Clinical Trials
Monday, June 18th, 2012
Thelancet.com: June 11, 2012. Citicoline is approved in some countries for the treatment of acute ischaemic stroke. The drug has shown some evidence of efficacy in a pooled analysis. We sought to confirm the efficacy of citicoline in a larger trial. Methods We undertook a randomised, placebo-controlled, sequential trial in patients with moderate-to-severe acute ischaemic […]
Clinical Trials
Monday, June 18th, 2012
Archinte.jamanetwork.com: June 4, 2012. Nearly 100 years have passed since a Dutch merchant first astonished Dr Karel Wenckebach with the ability to terminate episodes of atrial fibrillation (AF) through self-medication with quinine.1 Following this initial account of chemical cardioversion, maintenance of sinus rhythm gradually emerged as the preferred but unproven approach to the management of AF. […]
Clinical Trials
Monday, June 18th, 2012
Circ.ahajournals.org: May 9, 2012. Background—Patients with acute coronary syndromes and history of stroke or transient ischemic attack (TIA) have an increased rate of recurrent cardiac events and intracranial hemorrhages. Methods and Results—We evaluated treatment effects of ticagrelor versus clopidogrel in patients with acute coronary syndrome with and without a history of prior stroke or TIA […]
Clinical Trials
Friday, June 8th, 2012
Circep.ahajournals.org: June 5, 2012. Background—In animal models of atrial fibrillation (AF), changes in atrial electrophysiologic (EP) properties are associated with the development of AF. Their relevance to human AF is unclear. Methods and Results—The ASSERT trial enrolled 2580 patients receiving a dual-chamber pacemaker, who were over the age of 65 years and had a history of […]
Clinical Trials
Friday, June 8th, 2012
Pittsburgh.cbslocal.com: June 4, 2012 5:45 PM PITTSBURGH (KDKA) – Injecting stem cells into the brain of someone who has had a stroke is a hot button issue. Is it safe? Can it be done? That’s what researchers at the University of Pittsburgh are trying to find out. “Because these are cells that have not been injected […]
Clinical Trials
Friday, June 8th, 2012
Medpagetoday.com: By Michael Smith, North American Correspondent, MedPage Today, Published: June 03, 2012. CHICAGO — Cancer patients with lower incomes are markedly less likely to say they’re willing to take part in a clinical trial, a researcher said here. In an Internet-based survey, 9% of people with newly diagnosed cancers said they were taking part in a […]
Clinical Trials
Friday, June 8th, 2012
Neuronext.org: March 27th, 2012. The Network for Excellence in Neuroscience Clinical Trials, or NeuroNEXT, was created to conduct studies of treatments for neurological diseases through partnerships with academia, private foundations, and industry. The network is designed to expand the National Institute of Neurological Disorders and Stroke’s (NINDS) capability to test promising new therapies, increase the […]
Clinical Trials
Saturday, June 2nd, 2012
Biomedcentral.com: May 30, 2012 Clinical trials are the primary mechanism for advancing clinical care and evidenced-based practice, yet challenges with the recruitment of participants for such trials are widely recognized as a major barrier to these types of studies. Data warehouses store large amounts of heterogenous clinical data that can be used to enhance recruitment practices, […]
Clinical Trials
Saturday, June 2nd, 2012
A Randomized, Controlled Trial Stroke.ahajournals.org: May 24, 2012. Background and Purpose—To determine the effect of a multifaceted stroke telerehabilitation (STeleR) intervention on physical function, and secondarily on disability, in veterans poststroke. Methods—We conducted a prospective, randomized, multisite, single-blinded trial in 52 veterans with stroke from 3 Veterans Affairs medical centers. Veterans with a stroke in the […]
Clinical Trials
Saturday, June 2nd, 2012
Stroke.ahajournals.org: May 24, 2012 Background and Purpose—The Scandinavian Candesartan Acute Stroke Trial (SCAST) found no benefits of candesartan in acute stroke. In the present analysis we aim to investigate the effect of change in blood pressure during the first 2 days of stroke on the risk of early adverse events and poor outcome. Methods—SCAST was a […]
