HEALTH: Cost of clinical trials worries donors

Irinnews.org: LONDON, 24 May 2012 (IRIN) – The more medical successes there are, the more it costs to find the next one, prompting donors to demand more from researchers carrying out large-scale trials of drugs, vaccines and global health impacts. “As a funder, I hate clinical trial applications,” said Jimmy Whitworth, head of international activities at […]

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

The Lancet, Early Online Publication, 23 May 201. Background Thrombolysis is of net benefit in patients with acute ischaemic stroke, who are younger than 80 years of age and are treated within 4·5 h of onset. The third International Stroke Trial (IST-3) sought to determine whether a wider range of patients might benefit up to […]

Clinical Trials 101

Stroke.org: 5/22/2012. Should you participate? What to know before you sign up Patients interested in new and alternative medical therapies for stroke treatment often look into clinical research opportunities. In fact, post-stroke clinical trials are seeing increased participation each year. During a clinical trial, experimental medicines and medical devices undergo a multi-phase, Food and Drug Administration […]

Feasibility of Prehospital Teleconsultation in Acute Stroke – A Pilot Study in Clinical Routine

Plosone.org: 5/18/2012. Inter-hospital teleconsultation improves stroke care. To transfer this concept into the emergency medical service (EMS), the feasibility and effects of prehospital teleconsultation were investigated. Methodology/Principal Findings Teleconsultation enabling audio communication, real-time video streaming, vital data and still picture transmission was conducted between an ambulance and a teleconsultation center. Pre-notification of the hospital was carried […]

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

The Lancet, Early Online Publication, 17 May 2012. Statins reduce LDL cholesterol and prevent vascular events, but their net effects in people at low risk of vascular events remain uncertain. Methods This meta-analysis included individual participant data from 22 trials of statin versus control (n=134537; mean LDL cholesterol difference 1.08 mmol/L; median follow-up 4.8 years) […]

Recent Clinical Trials in Atrial Fibrillation in Hypertensive Patients

springerlink.com:  5/11/2012. Athanasios J. Manolis, Manolis S. Kallistratos and Leonidas E. Poulimenos Current Hypertension Reports, Online First™, 11 May 2012 Read More

Paralyzed individuals use thought-controlled robotic arm to reach and grasp

NIH-funded study shows progress in brain-computer interface technology Nnih.gov: Wednesday, May 16, 2012. In an ongoing clinical trial, a paralyzed woman was able to reach for and sip from a drink on her own – for the first time in nearly 15 years – by using her thoughts to direct a robotic arm. The trial, funded […]

Statin Therapy and the Risk of Intracerebral Hemorrhage

A Meta-Analysis of 31 Randomized Controlled Trials Stroke.ahajournals.org: May 15, 2012. Background and Purpose—Statin therapy decreases the risk of ischemic stroke. An increased risk of intracerebral hemorrhage (ICH) has been observed in some studies. To investigate this issue, we performed a meta-analysis of randomized controlled trials using statins that reported ICH. Methods—We performed a literature search […]

Texas stem cell rules may impede clinical research

The Lancet: by Carrie Arnold, May 12, 2012. Stem cell researchers in the USA and abroad are reeling from new laws in Texas that commercialise experimental procedures and could attract patients away from clinical trials. Carrie Arnold reports. New regulations on the experimental use of adult stem cells recently passed by the Texas Medical Board has […]

Study Reports Catheter Ablation Superior to Drug Therapy as First-Line Treatment for Atrial Fibrillation

Preliminary Findings Presented at Heart Rhythm Society’s Annual Scientific Meeting BOSTON–(BUSINESS WIRE): May 11, 2012 08:00 AM. Patients with the heart rhythm disorder atrial fibrillation (AFib) who received first-line catheter ablation treatment had a longer arrhythmia-free interval than patients receiving antiarrhythmic drugs, the standard first-line treatment. The preliminary findings were presented during a late-breaking session […]

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