Poststroke Outcomes Vary by Pathogenic Stroke Subtype in The Atherosclerosis Risk in Communities Study

STROKEAHA: May 16, 2013 Background and Purpose—Early risk of recurrence and mortality after stroke differs by subtype, but less is known about long-term recurrence and hospital readmissions. These differences have economic implications and will affect long-term disability and stroke survivor quality of life. We examined recurrent stroke, all-cause hospital readmission, and mortality by index pathogenic subtype. […]

Epidemiology of stroke and its subtypes in Chinese vs white populations

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Neurology: July 16, 2013 Objective: We aimed to systematically assess the evidence for differences in the incidence of stroke and distribution of its subtypes in Chinese compared with white populations. Methods: We comprehensively sought studies conducted since 1990 in Chinese populations of 1) first-ever stroke incidence (community-based studies only), and 2) pathologic types/subtypes of stroke (hospital- or community-based […]

Gene Signature Predicts Aspirin Resistance

asprin

National Institutes of Health: July 16th, 2013 About 60 million Americans take an aspirin a day to reduce the risk of strokes and heart attacks. But for 10 to 30% of those who follow this recommendation, this preventive therapy turns out not to offer any protection. An NIH-funded team, based at Duke University Medical Center, has […]

Overlap of Diseases Underlying Ischemic Stroke

  STROKEAHA: 7/16/13 The ASCOD Phenotyping   Background and Purpose—ASCOD phenotyping (A, atherosclerosis; S, small vessel disease; C, cardiac pathology; O, other causes; and D, dissection) assigns a degree of likelihood to every potential cause (1 for potentially causal, 2 for causality is uncertain, 3 for unlikely causal but disease is present, 0 for absence of […]

Adherence to antihypertensive therapy prior to the first presentation of stroke in hypertensive adults: population-based study

Eur Heart J : 7/16/13 Aims Antihypertensive drug therapy is a major strategy of stroke prevention among hypertensive patients. The aim of this study was to estimate the excess risk of stroke associated with non-adherence to antihypertensive drug therapy among hypertensive patients. Methods and results We conducted a population-based study using records from Finnish national registers for 1 January […]

Antithrombotic drugs and risk of hemorrhagic stroke in the general population

Neurology: 7/10/13 Objective: To investigate the relationship between hemorrhagic stroke and use of antiplatelets and warfarin using data from The Health Improvement Network. Methods: A total of 1,797 incident cases of intracerebral hemorrhage (ICH) and 1,340 of subarachnoid hemorrhage (SAH) were ascertained. Density-based sampling was used to select 10,000 controls free from hemorrhagic stroke. Risk of hemorrhagic stroke […]

A simple 8-point score strongly predicts early outcomes in acute stroke

Ischemic Stroke

Wiley:  7/9/13 Previous prognostic scoring systems in predicting stroke mortality are complex, require multiple measures that vary with time and failed to produce a simple scoring system. Aims/Hypothesis The study aims to derive and internally validate a stroke prognostic scoring system to predict early mortality and hospital length of stay. Read More

Relevance of stroke subtype in vascular risk prediction

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Neurology: July 3, 2013 Objective: To ascertain the risk of a new vascular event (NVE) occurring after ischemic stroke and evaluate differences in risk based on stroke subtype. Methods: This was a prospective observational study of consecutive patients with nonfatal stroke recruited at a single tertiary stroke center with follow-up ranging from 2 to 5 years (average, 31 […]

Satisfaction With Palliative Care After Stroke

STROKEAHA: July 2, 2013 Background and Purpose—The determinants of satisfaction for families of acute stroke patients receiving palliative care have not been extensively studied. We surveyed families to determine how they perceived palliative care after stroke. Methods—Families of patients palliated after ischemic stroke, intracerebral, or subarachnoid hemorrhage were approached. Four weeks after the patient’s death, families […]

Accuracy of clinician vs risk score prediction of ischemic stroke outcomes

Neurology: June 28, 2013 Objective: We compared the accuracy of clinicians and a risk score (iScore) to predict observed outcomes following an acute ischemic stroke. Methods: The JURaSSiC (Clinician JUdgment vs Risk Score to predict Stroke outComes) study assigned 111 clinicians with expertise in acute stroke care to predict the probability of outcomes of 5 ischemic stroke case […]

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