News
Monday, October 22nd, 2012
Neurology: October 17, 2012 We synthesized the epidemiologic evidence concerning selective serotonin reuptake inhibitor (SSRI) exposure and the risk of CNS hemorrhage. Methods: We searched for controlled observational studies comparing SSRI therapy with a control group not receiving SSRIs. We used DerSimonian and Laird fixed effect models to compute summary risk associations. Results: Intracranial hemorrhage was related to […]
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Monday, October 22nd, 2012
Jama: October 15, 2012 We sought to develop and validate a simple clinical prediction rule for death and severe disability after acute ischemic stroke that can be used by general clinicians at the time of hospital admission. Methods We analyzed data from a registry of 9847 patients (4943 in the derivation cohort and 4904 in the […]
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Monday, October 22nd, 2012
Environmental Health: October 15, 2012 While several studies have investigated the effects of short-term air pollution on cardiovascular disease, less is known about its effects on cerebrovascular disease, including stroke and transient ischaemic attack (TIA). The aim of the study was to assess the effects of short-term variation in air pollutants on the onset of TIA […]
News
Monday, October 22nd, 2012
Neurology: October 10, 2012 We aimed to study various measures of blood pressure (BP) in the subacute phase of ischemic stroke to determine whether any of them predicted clinical outcome. Methods: In this retrospective observational study, a consecutive series of patients hospitalized for ischemic stroke within 48 hours of onset were enrolled. The subacute stage of stroke […]
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Monday, October 22nd, 2012
The New York Times Company: SEPTEMBER 15, 2011 Can an apple a day keep away stroke? The old adage promoting an apple a day for better health just got a boost from science. A large Dutch study has found that eating apples and pears is associated with a lower risk of stroke. The findings counter […]
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Thursday, October 11th, 2012
Neurology.org: 10/10/12 Objectives: We describe temporal trends in stroke incidence stratified by age from our population-based stroke epidemiology study. We hypothesized that stroke incidence in younger adults (age 20–54) increased over time, most notably between 1999 and 2005. Methods: The Greater Cincinnati/Northern Kentucky region includes an estimated population of 1.3 million. Strokes were ascertained in the population […]
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Thursday, October 11th, 2012
Neurology.org: 10/9/12 Objective: Intake of fruits and vegetables and levels of serum carotenoids have been associated with decreased risk of stroke, but the results have been inconsistent. The aim of the present study was to examine whether serum concentrations of major carotenoids, α-tocopherol and retinol, are related to any stroke and ischemic stroke in men. Methods: The […]
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Thursday, October 11th, 2012
Plosone.org: 10/8/12 Background and Purpose Major depressive disorder (MDD) is characterized by recurrent depressive episodes and one of the treatment choices is antidepressants. Patients with MDD are at greater risk of developing major metabolic diseases that may in turn lead to stroke. Moreover, both depressive symptoms and taking antidepressant medications are associated with higher risk […]
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Thursday, October 11th, 2012
Thelancet.com: 10/5/12 Background Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim of validating associations from previous GWAS and identifying novel genetic associations through meta-analysis of GWAS datasets for […]
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Thursday, October 11th, 2012
Stroke.ahajournals.org: 10/4/12 Background and Purpose—The contribution of genetics to stroke risk, and whether this differs for different stroke subtypes, remains uncertain. Genomewide complex trait analysis allows heritability to be assessed from genomewide association study (GWAS) data. Previous candidate gene studies have identified many associations with stoke but whether these are important requires replication in large independent […]
