Freeze the Stroke

American Heart Association: July 17, 2012. Public Awareness Program for Immediate Detection of First Symptoms The capacity of the general population to identify stroke signs is a major determinant for success of prehospital emergency pathways. Previous educational strategies using the media were usually short-lived and expensive. Tailoring information programs for special subgroups like acute stroke relatives […]

Despite benefit, hospitals not always alerted of incoming stroke patients

American Heart Association: July 10, 2012. Study Highlights: Stroke patients receive faster treatment when emergency medical services (EMS) personnel notify hospitals a possible stroke patient is en route. However, emergency personnel fail to alert hospitals of incoming stroke patients in nearly one-third of cases. Researchers say improved stroke care systems can address geographical and other factors […]

Dementia in patients hospitalized with stroke: rates, time course, and clinico-pathologic factors

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Onlinelibrary.wiley.com: JULY 11, 2012. Stroke is a risk factor for dementia and dementia predisposes to stroke. Dementia prevalence in subjects with stroke is comparable with that seen in stroke-free subjects who are 10 years older. Although overall there is heterogeneity between studies of prestroke and poststroke dementia, stratifying by study method and clinical criteria (e.g. inclusion/exclusion […]

Dying for the Weekend A Retrospective Cohort Study on the Association Between Day of Hospital Presentation and the Quality and Safety of Stroke Care

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Archneur.jamanetwork.com: 7/9/12. Objective  To examine the association between day of admission and measures of the quality and safety of the care received by patients with stroke. Design  Retrospective cohort study of patients admitted to hospitals with stroke (codes I60-I64 from theInternational Statistical Classification of Diseases and Related Health Problems, Tenth Version) from April 1, 2009, through […]

Association Between Major Perioperative Hemorrhage and Stroke or Q-Wave Myocardial Infarction

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Stroke.ahajournals.org: July 7, 2012. We examined the association between major perioperative hemorrhage and stroke or myocardial infarction among adults who underwent surgery from 2005 through 2009 at centers participating in the National Surgical Quality Improvement Program. We excluded patients with emergent, trauma-related, transplantation, cardiac, or neurological operations. Major hemorrhage was defined as bleeding necessitating transfusion […]

Patients Living in Impoverished Areas Have More Severe Ischemic Strokes

Stroke.ahajournals.org: July 5, 2012. Background and Purpose—Initial stroke severity is one of the strongest predictors of eventual stroke outcome. However, predictors of initial stroke severity have not been well-described within a population. We hypothesized that poorer patients would have a higher initial stroke severity on presentation to medical attention. Methods—We identified all cases of hospital-ascertained […]

Assessing the Integrity of Corticospinal Pathways From Primary and Secondary Cortical Motor Areas After Stroke

Stroke.ahajournals.org: July 3, 2012. Background and Purpose—Aside from the primary motor cortex, the corticospinal tract (CST) also receives fibers from dorsal and ventral premotor cortices and supplementary motor area, all of which might potentially contribute to motor function after stroke. We sought to quantify the microstructural integrity of CST originating from the hand representations in these […]

A modified Essen stroke risk score for predicting recurrent cardiovascular events: development and validation

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Onlinelibrary.wiley.com: 7/3/12. The Essen stroke risk score is widely applied to predict the risk of recurrent ischemic stroke. We developed a modified Essen stroke risk score and validated it using a large prospective Effective Vascular Event REduction after STroke (EVEREST) registry including 3588 patients with ischemic stroke in Japan. Patients with cardioembolic stroke were excluded, and […]

Genetic Variation Within the Interleukin-1 Gene Cluster and Ischemic Stroke

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Stroke.ahajournals.org: June 28, 2012. Evidence is emerging that inflammation plays a key role in the pathophysiology of ischemic stroke (IS). The aim of this study was to investigate whether genetic variation in the interleukin-1α, interleukin-1β, and interleukin-1 receptor antagonist genes (IL1A, IL1B, and IL1RN) is associated with IS and/or any etiologic subtype of IS. Methods—Twelve tagSNPs were analyzed […]

Etiology of stroke and choice of models

Onlinelibrary.wiley.com: 6/19/12. Animal models of stroke contribute to the development of better stroke prevention and treatment through studies investigating the pathophysiology of different stroke subtypes and by testing promising treatments before trials in humans. There are two broad types of animal models: those in which stroke is induced through artificial means, modeling the consequences of a […]

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