Therapies
Thursday, October 10th, 2013
J NeuroIntervent Surg: 10.9.13 Background and purpose The relationship between dense packing and incidence of angiographic recurrence after endovascular treatment of intracranial aneurysms has been shown but remains controversial. We retrospectively analyzed intracranial aneurysms treated with detachable coils to determine the relation between aneurysm volume, packing, and recurrence. Methods We reviewed 221 aneurysms in 199 patients who […]
Guidelines, Therapies
Thursday, October 10th, 2013
Implementation Science: October 1, 2013 Background Multiple guidelines are often available to inform practice in complex interventions. Guidance implementation may be facilitated if it is tailored to particular clinical issues and contexts. It should also aim to specify all elements of interventions that may mediate and modify effectiveness, including both their content and delivery. We conducted […]
Therapies
Friday, October 4th, 2013
STROKEAHA: October 3, 2013 Background and Purpose—The European Cooperative Acute Stroke Study (ECASS) III showed benefit of intravenous tissue-type plasminogen activator for acute ischemic stroke 3 to 4.5 hours from onset in selected patients from Europe, with this extended treatment subsequently recommended by the American Stroke Association. We prospectively enrolled patients with acute ischemic stroke treated […]
Therapies
Friday, October 4th, 2013
BMJ: October 1, 2013 Objective To determine the comparative effectiveness of exercise versus drug interventions on mortality outcomes. Design Metaepidemiological study. Eligibility criteria Meta-analyses of randomised controlled trials with mortality outcomes comparing the effectiveness of exercise and drug interventions with each other or with control (placebo or usual care). Data sources Medline and Cochrane Database of Systematic Reviews, May 2013. […]
Therapies
Friday, October 4th, 2013
Annals: October 2013 Background: Dual-antiplatelet regimens for prevention of recurrent stroke promote antithrombotic effects but may increase the risk for hemorrhage. Purpose: To qualitatively and quantitatively examine the risk for recurrent stroke and intracranial hemorrhage (ICH) linked to long-term dual- and single-antiplatelet therapy among patients with ischemic stroke and transient ischemic attack. Data Sources: PubMed, EMBASE, and the Cochrane Central […]
Therapies
Friday, October 4th, 2013
Neurosurgery: October 2013 BACKGROUND: Stroke is a leading cause of death and disability in the United States. Despite the proven benefits of intravenous tissue plasminogen activator (IV-tPA), only a small percentage of patients who have had a stroke (3.4%–5.2%) receive this US Food and Drug Administration-approved therapy. OBJECTIVE: To prospectively assess the impact of a telestroke […]
Guidelines, Therapies
Friday, October 4th, 2013
NHLBI Announcement: Cardiovascular Guidelines: October 2013 When he dedicated the new National Institutes of Health (NIH) Bethesda campus in October 1940, President Franklin D. Roosevelt declared, “We cannot be a strong nation unless we are a healthy nation. And so we must recruit knowledge and science in the service of national strength” 1. For more than 65 years, […]
Therapies
Friday, September 27th, 2013
CDC: 9/26/13 Introduction Quality improvement collaboratives are a popular model used to address gaps between evidence-based practice and patient care. Little is known about use of such collaboratives in emergency medical services, particularly for improving prehospital stroke care. To determine the feasibility of using this approach to improve prehospital stroke care, we conducted a pilot […]
Therapies
Friday, September 27th, 2013
STROKEAHA: September 24, 2013 Background and Purpose—Patients with any type of stroke managed in organized inpatient (stroke unit) care are more likely to survive, return home, and regain independence. However, it is uncertain whether these benefits apply equally to patients with intracerebral hemorrhage and ischemic stroke. Methods—We conducted a secondary analysis of a systematic review of […]
Therapies
Friday, September 27th, 2013
J NeuroIntervent Surg: 9/23/13 Stroke center designation is an integral component of maintaining the systems of care for cerebrovascular diseases.1 Organization of hospitals into efficient vehicles of healthcare delivery helps improve clinical outcomes.2 The approval of IV tissue plasminogen activator (tPA) for acute ischemic stroke (AIS) highlighted the need for specialized stroke centers able to quickly mobilize all […]
