Neurology: 8/14/13 Approximately 15% of all ischemic strokes (IS) occur in young adults and adolescents. To date, only limited prior public health and research efforts have specifically addressed stroke in the young. Early diagnosis remains challenging because of the lack of awareness and the relative infrequency of stroke compared with stroke mimics. Moreover, the causes of […]
Wiley: 8/8/13 We review recent advances in the treatment and prevention of acute ischemic stroke, including the current state of endovascular therapy in light of five randomized controlled trials published this past year. Although no benefit of endovascular therapy over IV t-PA has been demonstrated, endovascular therapy is an appropriate treatment for acute ischemic stroke patients […]
Ahajournals: 8/5/13 The cardiac surgical operating room (OR) is a complex environment in which highly trained subspecialists interact with each other using sophisticated equipment to care for patients with severe cardiac disease and significant comorbidities. Thousands of patient lives have been saved or significantly improved with the advent of modern cardiac surgery. Indeed, both mortality and morbidity for coronary artery bypass surgery […]
STROKEAHA: July 30, 2013 Background and Purpose—Studies in the United States and Canada have demonstrated socioeconomic gradients in outcomes of acute life-threatening cardiovascular and cerebrovascular diseases. The extent to which these findings are applicable to subarachnoid hemorrhage is uncertain. This study investigated socioeconomic status-related differences in risk of inpatient mortality and use of institutional postacute care […]
STROKEAHA: July 30, 2013 Background and Purpose—National registration studies (the Japanese Registry of Neuroendovascular Therapy [JR-NET] and JR-NET2) have determined the current status and outcomes of neuroendovascular therapy (neuro-EVT). We analyzed short-term outcomes of EVT for asymptomatic unruptured intracranial aneurysms (UIAs). Methods—We extracted periprocedural information about EVT for 4767 asymptomatic UIAs from 31 968 registered procedural […]
STROKEAHA: July 25, 2013 Background and Purpose—It is unknown whether new-extraischemic microbleeds (new-EMBs) develop rapidly after tissue-type plasminogen activator (tPA) infusion. We hypothesized that new-EMBs may develop rapidly after tPA infusion using T2*-weighted MRI (T2*) and investigated the frequency and clinical factors associated with new-EMBs. Methods—Patients with acute stroke within 3 hours of onset who were […]
STROKEAHA: July 25, 2013 Background and Purpose—A recent meta-analysis showed that women with acute ischemic stroke are less likely to receive treatment with intravenous alteplase than men. The aim of this study was to assess sex differences in treatment with intravenous alteplase and to explore the reasons for these differences. Methods—We analyzed data from the Promoting […]
STROKEAHA: July 25, 2013 A Pooled Analysis of 10 Dedicated Stroke Centers Background and Purpose—Inverse relationship between onset-to-door time (ODT) and door-to-needle time (DNT) in stroke thrombolysis was reported from various registries. We analyzed this relationship and other determinants of DNT in dedicated stroke centers. Methods—Prospectively collected data of consecutive ischemic stroke patients from 10 […]
STROKEAHA: July 25, 2013 Background and Purpose—The ischemic stroke risk score (iScore) is a validated tool developed to estimate the risk of death and functional outcomes early after an acute ischemic stroke. Our goal was to determine the ability of the iScore to estimate clinical outcomes after intravenous thrombolysis tissue-type plasminogen activator (tPA) in the Virtual […]
Wiley: JUL 23, 2013 Background Recent epidemiological studies have demonstrated an association between perceived psychological stress and ischemic stroke. A feature of stroke is recurrence; 30–40% within five-years following first transient ischemic attack/stroke. Equipping patients with skills and coping strategies to help reduce or manage perceived psychological stress may represent an important secondary prevention intervention. Mindfulness-based […]
