Therapies
Monday, June 3rd, 2013
The Lancet Neurology: June 1. 2013 Early recanalisation and an increase in collateral blood supply are predictors of favourable outcome in acute ischaemic stroke. Since individual responses to intravenous treatment with alteplase are heterogeneous, additional intra-arterial thrombolytic and mechanical endovascular treatment is increasingly given. Despite encouraging findings from single-centre studies, data from randomised clinical trials have […]
Therapies
Monday, June 3rd, 2013
The Lancet Neurology: June 1. 2013 Thrombolysis with alteplase administered within a narrow therapeutic window provides an effective therapy for acute ischaemic stroke. However, mainly because of prehospital delay, patients often arrive too late for treatment, and no more than 1—8% of patients with stroke obtain this treatment. We recommend that all links in the prehospital […]
Therapies
Monday, June 3rd, 2013
International Journal of Stroke: May 22, 2013 Background Low-frequency repetitive transcranial magnetic stimulation of the nonlesional hemisphere combined with occupational therapy significantly improves motor function of the affected upper limb in poststroke hemiparetic patients, but the recovery mechanism remains unclear. Aims To investigate the recovery mechanism using functional magnetic resonance imaging. Methods Forty-seven poststroke hemiparetic […]
Therapies
Monday, June 3rd, 2013
STROKEAHA: May 16, 2013 Background and Purpose—Use of endovascular coiling for treatment of ruptured and unruptured intracranial aneurysms (IAs) in the elderly is increasing. We performed a meta-analysis of the literature examining clinical and angiographic outcomes for treatment of IAs in the elderly. Methods—We performed a comprehensive review of the literature from 1995 to 2012, reporting […]
Therapies
Wednesday, May 29th, 2013
The Lancet Neurology: June 1, 2013 Early recanalisation and an increase in collateral blood supply are predictors of favourable outcome in acute ischaemic stroke. Since individual responses to intravenous treatment with alteplase are heterogeneous, additional intra-arterial thrombolytic and mechanical endovascular treatment is increasingly given. Despite encouraging findings from single-centre studies, data from randomised clinical trials […]
Therapies
Wednesday, May 29th, 2013
The Lancet Neurology: June 1, 2013 Thrombolysis with alteplase administered within a narrow therapeutic window provides an effective therapy for acute ischaemic stroke. However, mainly because of prehospital delay, patients often arrive too late for treatment, and no more than 1—8% of patients with stroke obtain this treatment. Read more
Therapies
Wednesday, May 29th, 2013
STROKEAHA: May 23, 2013 Background and Purpose—To investigate relationships between the degree of early reperfusion achieved on perfusion-weighted imaging and clinical outcomes in the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution studies. We hypothesized that there would be a strong correlation between the degree of reperfusion achieved and clinical outcomes in target mismatch (TMM) […]
Therapies
Wednesday, May 29th, 2013
International Journal of Stroke: May 22, 2013 Background Low-frequency repetitive transcranial magnetic stimulation of the nonlesional hemisphere combined with occupational therapy significantly improves motor function of the affected upper limb in poststroke hemiparetic patients, but the recovery mechanism remains unclear. Aims To investigate the recovery mechanism using functional magnetic resonance imaging. Read more
Therapies
Wednesday, May 29th, 2013
STROKEAHA: May 16, 2013 Background and Purpose—Use of endovascular coiling for treatment of ruptured and unruptured intracranial aneurysms (IAs) in the elderly is increasing. We performed a meta-analysis of the literature examining clinical and angiographic outcomes for treatment of IAs in the elderly. Methods—We performed a comprehensive review of the literature from 1995 to 2012, reporting […]
Therapies
Friday, May 17th, 2013
STROKEAHA: May 14, 2013 Background and Purpose—Sex and race reportedly influence outcome after recombinant tissue-type plasminogen activator (rtPA). It is, however, unclear whether baseline imbalances (eg, stroke severity) or lack of response to thrombolysis is responsible. We applied balancing methods to test the hypothesis that race and sex influence outcome after rtPA independent of baseline […]
